2. On the replication bubble below, draw the newly synthesized strands of DNA as they would be seen before the actions of DNA polymerase I and DNA ligase. Label (or color code) each of the following on your drawing: -the origin of replication -the leading strand(s) -the lagging strand(s) -the 5' and 3' ends of each newly synthesized DNA fragment -Okazaki fragments -RNA primers -the current location(s) of DNA helicase -the current location(s) of DNA polymerase III 35 5

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question 2
e. Suppose some G1-S Cyclin/Cdks were damaged and unable to function properly. Do you expect
this would increase or decrease the rate of cell division?
mytheres of DNA
Decrease as
it would disrupt the
f. The chemical modification made by the G1-S Cdks on DNA polymerase will be removed at
some point. What class of enzyme do you expect to remove the chemical modification?
Phosphatase
2. On the replication bubble below, draw the newly synthesized strands of DNA as they would be seen before the actions
of DNA polymerase I and DNA ligase.
Label (or color code) each of the following on your drawing:
-the origin of replication
-the leading strand(s)
-the lagging strand(s)
-the 5' and 3' ends of each newly synthesized DNA fragment
-Okazaki fragments
-RNA primers
-the current location(s) of DNA helicase
-the current location(s) of DNA polymerase III
3. Now consider the following diagram, where two replication bubbles are about to meet.
5
...... الله [
leading strand
11
logging strand
3
Draw in the strands of newly synthesized DNA as you did in question 2.
E
35
3
a leading strand
legging strand
5
2
Transcribed Image Text:e. Suppose some G1-S Cyclin/Cdks were damaged and unable to function properly. Do you expect this would increase or decrease the rate of cell division? mytheres of DNA Decrease as it would disrupt the f. The chemical modification made by the G1-S Cdks on DNA polymerase will be removed at some point. What class of enzyme do you expect to remove the chemical modification? Phosphatase 2. On the replication bubble below, draw the newly synthesized strands of DNA as they would be seen before the actions of DNA polymerase I and DNA ligase. Label (or color code) each of the following on your drawing: -the origin of replication -the leading strand(s) -the lagging strand(s) -the 5' and 3' ends of each newly synthesized DNA fragment -Okazaki fragments -RNA primers -the current location(s) of DNA helicase -the current location(s) of DNA polymerase III 3. Now consider the following diagram, where two replication bubbles are about to meet. 5 ...... الله [ leading strand 11 logging strand 3 Draw in the strands of newly synthesized DNA as you did in question 2. E 35 3 a leading strand legging strand 5 2
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