2. It is desired to examine the kinetic properties of voltage-dependent potassium channels in a ventricular cardiomyocyte. A patch - clamp experimental protocol was designed for this purpose. However, when they prepared intracellular and extracellular solutions in physiological conditions, they observed sodium, potassium and calcium currents simultaneously. In this case, they could not obtain a pure potassium channel current. b. What would you say about the voltage - and time - dependent inhibition properties of potassium channels?

Human Anatomy & Physiology (11th Edition)
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2. It is desired to examine the kinetic properties of
voltage-dependent potassium channels in a ventricular
cardiomyocyte. A patch - clamp experimental protocol
was designed for this purpose. However, when they
prepared intracellular and extracellular solutions in
physiological conditions, they observed sodium,
potassium and calcium currents simultaneously. In this
case, they could not obtain a pure potassium channel
current. b. What would you say about the voltage -
and time - dependent inhibition properties of potassium
channels?
Transcribed Image Text:2. It is desired to examine the kinetic properties of voltage-dependent potassium channels in a ventricular cardiomyocyte. A patch - clamp experimental protocol was designed for this purpose. However, when they prepared intracellular and extracellular solutions in physiological conditions, they observed sodium, potassium and calcium currents simultaneously. In this case, they could not obtain a pure potassium channel current. b. What would you say about the voltage - and time - dependent inhibition properties of potassium channels?
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