2. Draw the 4 bromonium intermediates formed in the following reaction. On each, indicate which carbon(s) will be attacked by the nucleophilic methanol. + Br2 MeOH show the four bromonium intermediates and place a star (*) near the electrophilic Cs 3. Predict the products of the following reaction, including stereoisomers.

The mechanism proceeds through a first cationic intermediate, intermediate 1. Nucleophilic attack leads to intermediate 2, which goes on to form the final product. In cases that involve negatively charged nucleophile, the attack of the nucleophile leads directly to the product. H. Br + CH3OH Br Intermediate 2 (product) Intermediate 1 In a similar fashion, draw intermediate 1 and intermediate 2 (final product) for the following reaction. OCH3 Cl2 MEOH ĆI racemic mixture Pay attention to the reactants, they may differ from the examples. In some reactions, one part of the molecule acts as the nucleophile. • You do not have to consider stereochemistry. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate intermediate 1 and intermediate 2 using the the dropdown menu. → symbol from

3. Draw the mechanism for the following elimination reaction. Be sure to clearly show the configuration of the substrate during elimination and the stereochemistry of the final product. Ph Br F Bri H NaOCH₂ HOCH, NaOCH, HOCH,

3. Why do the following two reactions not proceed under basic conditions? Draw the mechanism of each up until the point of failure under basic conditions. HO * OH 4 basic conditions HN Ph * basic conditions

Please help with this

Predict the products for each of the following reactions. Draw the transition state to show how the product is formed. Meo, COOH H. HOOC Meo II

Answer the questions below with reference to the reaction shown here: Meo. `OH 2 Meo AICI3 (a) The reaction involves the initial formation of an "acylium ion" from 2: draw the mechanism for the formation of this ion. (b) Draw the structure of the intermediate formed when the acylium ion reacts with compound 1, and then show by means of curved arrows how this intermediate is transformed to the final product 3. (You do not need to show all the resonance forms of the intermediate.) Explain why the substitution takes place ortho to the OMe (c) substituent and not ortho to the methyl substituent.

5a) Draw the product(s) of the reaction shown below. Additionally, identify the nucleophile, electrophile and leaving group.

Draw the alkyl bromide for reaction 2. Select Draw Rings More Erase | 7 | | H Br Reagents Carboxylic Acid Product 1. Diethyl malonate, NaOC2H5, C2H5OH 2. NaOH, H2O 3. H3O*, heat ОН Draw the alkyl bromide for reaction 3.

Chemistry I think I understand most of this except for what mechanisms these resemble. Thanks!