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2. ALL are true about the activity of Macrolides EXCEPT: * It is effective against syphilis infections it is very effective against G(-) bacteria O it is effective against erysipelas infections O it resembles that of penicillin 3. These are ALL causes of bacterial resistance against macrolides EXCEPT: * modification of binding site release of esterases O active efflux O bacterial endospores

2. ALL are true about the activity of Macrolides EXCEPT: * It is effective against syphilis infections it is very effective against G(-) bacteria O it is effective against erysipelas infections O it resembles that of penicillin 3. These are ALL causes of bacterial resistance against macrolides EXCEPT: * modification of binding site release of esterases O active efflux O bacterial endospores

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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7:42 1 by 8 974 2. ALL are true about the activity of Macrolides EXCEPT: * O It is effective against syphilis infections O it is very effective against G(-) bacteria O it is effective against erysipelas infections O it resembles that of penicillin 3. These are ALL causes of bacterial resistance against macrolides EXCEPT: * O modification of binding site O release of esterases O active efflux O bacterial endospores 4. These are ALL adverse effects of Erythromycin EXCEPT: * O Neutropenia O Hepatotoxicity O Acute cholestatic hepatitis O CYP450 inhibition 5. These are drugs that have prolonged half-life when taken with erythromycin EXCEPT: " O Rifampicin O Lanoxin Lasix O Lipitor 6. Definition of Clarithromycin O it is the 6-methyl ester of erythromycin it is the 6-methylene ether of erythromycin it is the 6-methyl ether of erythromycin O it is the 6-methylene ester of erythromycin 7. ALL are true about Azithromycin EXCEPT: * O it does not inactivate CYP450 enzymes O could be taken with food O has a long half life O has better pharmacokinetic properties than Clarithromycin O O O C
Transcribed Image Text:7:42 1 by 8 974 2. ALL are true about the activity of Macrolides EXCEPT: * O It is effective against syphilis infections O it is very effective against G(-) bacteria O it is effective against erysipelas infections O it resembles that of penicillin 3. These are ALL causes of bacterial resistance against macrolides EXCEPT: * O modification of binding site O release of esterases O active efflux O bacterial endospores 4. These are ALL adverse effects of Erythromycin EXCEPT: * O Neutropenia O Hepatotoxicity O Acute cholestatic hepatitis O CYP450 inhibition 5. These are drugs that have prolonged half-life when taken with erythromycin EXCEPT: " O Rifampicin O Lanoxin Lasix O Lipitor 6. Definition of Clarithromycin O it is the 6-methyl ester of erythromycin it is the 6-methylene ether of erythromycin it is the 6-methyl ether of erythromycin O it is the 6-methylene ester of erythromycin 7. ALL are true about Azithromycin EXCEPT: * O it does not inactivate CYP450 enzymes O could be taken with food O has a long half life O has better pharmacokinetic properties than Clarithromycin O O O C
7:42 1 Y 8 a. This is the rmicrebial source af Chlorarmphenical O Saccharoplyspora venezeualae O Streutunyces Streptarryces venezuelae O Saccharapelyspora crythreae O Streptomyces erythreae 9. Compound where chloramphenicol is derived from* O nitrobenzene molety O lacterie rirg O dishloroacetic acid O nitrobenzene molety end dichloroacetic ecic 10. Chloramphernicol has bac:tericidal activity against these bac:teria EXCEPT: R. ricketsii N. meningitiries O H. Influenzee B. fragilis 11. Condition where chloramphenicel is ineffective O Syphilis intection O pseudorronas infection O ponprheal infection O chlamydiel infection 12. Formulation of chloramphenicol that is palatable O chloramphenicol palmitate O chloramphenicol esalste O chloramphenicol chlorate O chlorariphenicol carborale 13. Substance which is a component of lincomycins O nitrobenzene O sulfur O amino euçare O lasters 14. Definition of Clindamycin O 7 hydra 7 diexy Lincomycin O 7-hydroxy-7-cecxy Lincomycin O 7-dchloro-7-aydroxy Lincemycin O 7-chloro-7-teuxy Lincomycin 15. Type of bacterla most susceptible to aminoglycosldes O Anaerobic G) O Aerobic. G(-) O Anaerobic G(+) O Aerobic G) o o o o o o C
Transcribed Image Text:7:42 1 Y 8 a. This is the rmicrebial source af Chlorarmphenical O Saccharoplyspora venezeualae O Streutunyces Streptarryces venezuelae O Saccharapelyspora crythreae O Streptomyces erythreae 9. Compound where chloramphenicol is derived from* O nitrobenzene molety O lacterie rirg O dishloroacetic acid O nitrobenzene molety end dichloroacetic ecic 10. Chloramphernicol has bac:tericidal activity against these bac:teria EXCEPT: R. ricketsii N. meningitiries O H. Influenzee B. fragilis 11. Condition where chloramphenicel is ineffective O Syphilis intection O pseudorronas infection O ponprheal infection O chlamydiel infection 12. Formulation of chloramphenicol that is palatable O chloramphenicol palmitate O chloramphenicol esalste O chloramphenicol chlorate O chlorariphenicol carborale 13. Substance which is a component of lincomycins O nitrobenzene O sulfur O amino euçare O lasters 14. Definition of Clindamycin O 7 hydra 7 diexy Lincomycin O 7-hydroxy-7-cecxy Lincomycin O 7-dchloro-7-aydroxy Lincemycin O 7-chloro-7-teuxy Lincomycin 15. Type of bacterla most susceptible to aminoglycosldes O Anaerobic G) O Aerobic. G(-) O Anaerobic G(+) O Aerobic G) o o o o o o C
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