2) Predict the major product(s) of the following reaction. Also, write the mechanism for the transformation. Br LDA diisopropylamine to (abubong nojam 9 tailben
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- please answer in words.18en the folbwng sequence of reac ond what wo structure of compound AT D (CH,,CULI 2) H,0 HN-CH, H,0 Select one 2.Wnchufthfollewine.comectly represert eet the stepm the rechnsnetamad altalcardensation reactNOC XT Ph CH₂ Both primary and secondary amines add to a ß-unsaturated aldehydes and ketones to yield ß-amino aldehydes and ketones rather than the alternative imines. Under typical reaction conditions, both direct and conjugate modes of addition occur rapidly. But because the reactions are reversible, they generally proceed with thermodynamic control rather than kinetic control so the more stable conjugate addition product is often obtained to the complete exclusion of the less stable direct addition product. Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions H H CH3NH₂ CH3 H-A :A Ph NHCH3 вон CH3 :A H-A 8b
- 4. Provide a mechanism for the following transformation: میلے NaOH H₂O, A H₂N NaUse the reaction given below to answer the following questions. A CH₂OH B H₂O+ C + CH3NH3* D a) What are the approximate pKas of compounds A and B? b) The reaction given above is irreversible. Give a detailed explanation of the reaction and reaction mechanism. Your explanation should indicate your knowledge of the reactivity of carboxylic acid derivatives.With sulfides are treated with α,β-unsaturated ketones and aldehydes, they can attackeither through direct or conjugate addition. Based on the NMR spectrum obtained fromthe product of the reaction below, indicate whether the reaction occurs by direct orconjugate addition and provide an arrow pushing mechanism