2 nm DNA double helix Linker Wrapping of DNA around histone (H1) a histone octamer 60 nm 11 nm Histone Nucleosome octamer (a) Nucleosomes ("beads on a string") 33 nm Formation of a three-dimensional zigzag or solenoid structure via histone H1 and nonhistone proteins 30 nm 200 nm (b) 30-nm fiber Anchoring of the 30-nm fiber to protein filaments to form radial loop domains (b) 30-nm fiber Anchoring of the 30-nm fiber to protein filaments to form radial loop domains 300 nm (c) Radial loop domains Protein filament Additional folding in which the radial loops are closely compacted. In a metaphase chromosome, the protein filaments form a scaffold that gives a chromosome its shape. pellnae 700 nm 180 nm Protein scaffold 1400 nm (d) Metaphase chromosome 640 nm

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Describe what structural changes convert a chromosomal region that is 300 nm in diameter to one that is 700 nm in diameter.

2 nm
DNA double helix
Linker
Wrapping of DNA around
histone (H1)
a histone octamer
60 nm
11 nm
Histone
Nucleosome
octamer
(a) Nucleosomes ("beads on a string")
33 nm
Formation of a three-dimensional zigzag
or solenoid structure via histone H1 and
nonhistone proteins
30 nm
200 nm
(b) 30-nm fiber
Anchoring of the 30-nm fiber to
protein filaments to form radial
loop domains
Transcribed Image Text:2 nm DNA double helix Linker Wrapping of DNA around histone (H1) a histone octamer 60 nm 11 nm Histone Nucleosome octamer (a) Nucleosomes ("beads on a string") 33 nm Formation of a three-dimensional zigzag or solenoid structure via histone H1 and nonhistone proteins 30 nm 200 nm (b) 30-nm fiber Anchoring of the 30-nm fiber to protein filaments to form radial loop domains
(b) 30-nm fiber
Anchoring of the 30-nm fiber to
protein filaments to form radial
loop domains
300 nm
(c) Radial loop domains
Protein filament
Additional folding in which
the radial loops are closely
compacted. In a metaphase
chromosome, the protein
filaments form a scaffold
that gives a chromosome
its shape.
pellnae
700 nm
180 nm
Protein
scaffold
1400 nm
(d) Metaphase chromosome
640 nm
Transcribed Image Text:(b) 30-nm fiber Anchoring of the 30-nm fiber to protein filaments to form radial loop domains 300 nm (c) Radial loop domains Protein filament Additional folding in which the radial loops are closely compacted. In a metaphase chromosome, the protein filaments form a scaffold that gives a chromosome its shape. pellnae 700 nm 180 nm Protein scaffold 1400 nm (d) Metaphase chromosome 640 nm
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