2) [50%] A carbohydrate-functionalized sensor for the capture of a specific protein, bacterial or viral target (e.g. a human milk glycan functionalized SPR chip for the capture of norovirus capsids). [HINT: Your sensor should be functionalized WITH a carbohydrate. The target molecule does not need to be a carbohydrate] 3) [50%] A DNA-functionalized sensor for the capture of a nucleic acid or DNA-binding protein (e.g. a DNA- functionalized microelectrode array for DNA hybridization). NOTE: For your two sensors, you must include a specific chemistry for surface modification, a specific surface capture molecule (protein, carbohydrate, and/or nucleic acid), and specific target molecule for detection. Example illustration (note, this is a VERY good example, you don't need to be a meticulous in your drawing) A conductance ▲ current Source Drain Gate FIGURE 3.4 A nano field effect transistor biosensor is shown schematically. The intrinsic electrical properties of biomolecules that bind to the functionalized semiconducting material (e.g., nanowire and carbon nanotube) changes its conductance and therefore influences the amount of current that flows from the source to the drain.
PLEASE have the following and help D:.
What i need for the chosen of 2/3 choices.
2) Illustrate detailed chemical scheme for how you will functionalize your
3) Include an illustration of the functional sensor, and describe whether the sensor is label-free or not, what signal is observed, and how you would detect the interaction (i.e. if a labeled antibody is required, you should describe what label would be needed). Don’t go overboard with detail, a single illustration would suffice (see attached illustration of the nano field effect transistor as an example).
4) Include a VERY brief (~150-200word) description of each platform, including what SPECIFIC interaction you would observe, and at least one reference of your choosing on the biosensor platform you are using. Details should include the SPECIFIC MEDICAL/RESEARCH NEED for the sensor, what it is detecting, and how that information can be used.
I chose the first 2. which was Protein-Functionalized QCM Sensor and Carbohydrate-Functionalized SPR Sensor.
Can you please help with Chem draw and the Illustration of the Functional Sensor for both of these.
![2) [50%] A carbohydrate-functionalized sensor for the capture of a specific protein, bacterial or viral target
(e.g. a human milk glycan functionalized SPR chip for the capture of norovirus capsids). [HINT: Your sensor should
be functionalized WITH a carbohydrate. The target molecule does not need to be a carbohydrate]
3) [50%] A DNA-functionalized sensor for the capture of a nucleic acid or DNA-binding protein (e.g. a DNA-
functionalized microelectrode array for DNA hybridization).
NOTE: For your two sensors, you must include a specific chemistry for surface modification, a specific
surface capture molecule (protein, carbohydrate, and/or nucleic acid), and specific target
molecule for detection.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F6f3e5576-0f79-4ac1-b31d-3e0bb619ebe7%2Fe236eab0-9058-4378-a55f-f2090a05881c%2Fnjy73ek_processed.jpeg&w=3840&q=75)
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