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- Explain how CDK activity is modulated by the following proteins: (a) cyclin, (b) CAK, (c) Wee1, (d) p21.Why would it be incorrect to refer to the formed elements as cells?I. The retinoic acid receptor (RAR) is a transcription factor that is similar to steroid hormone receptors. Thesubstance (ligand) that binds to this receptor is retinoicacid. One of the genes whose transcription is activatedby retinoic acid binding to the receptor is myoD. Thediagram that follows shows a schematic view of theRAR proteins produced by genes into which one oftwo different 12-base double-stranded oligonucleotides had been inserted in the ORF. The insertion site(a–m) associated with each mutant protein is indicatedwith the appropriate letter on the polypeptide map.For constructs encoding proteins a–e, oligonucleotide 1(5′ TTAATTAATTAA 3′ read off either strand) wasinserted into the RAR gene. For constructs encoding proteins f–m, oligonucleotide 2 (5′ CCGGCCGGCCGG 3′)was inserted into the gene.NH2 f g h i j k l m COOHa b c d eThe wild-type RAR protein can both bind DNA and activate transcription weakly in the absence of retinoic acid(RA) and strongly in RA’s presence. Each…
- (46) A mutated form of protein p5x is found in patients with squamous cell carcinoma. In vitro studies show that the normal p5x molecule binds to DNA, and neoplastic cells accumulate in the G0 phase of the cell cycle. In contrast, the mutated form of p5x does not bin d to DNA. These finding are most characteristics of which of the following? (A) Growht factor receptors (B) GTP-binding protein (C) Nonreceptor tyrosine kinases (D) Oncogene proteins (E) Tumor suppressor gene proteins8. Describe the MAP kinase activation pathwaywhy leucines are crucial part of GCN4 protein?
- 39. Stem cells transplanted from one person to another would havelessmedical complications. True FalsePlease ASAP. Thank you. What happens when Gαq proteins are stimulated?4:32 120-201 FA22 Homework 02 2.docx 10. When a primary signal needs to be sent to most cells throughout a multicellular organism, the signal most suited for this is a AG) neurotransmitter. AH) hormone. AI) dissolved gas. AJ) transcription factor. AK) translation elongation factor Answer: Explanation: 5G 100 AM) the steroid hormones AN) tyrosine-derived epinephrin and norepinephrin AO) serotonin and melatonin (tryptophan-derived mammalian neurotransmitters) 11. Hydrophobic primary messengers usually cause molecular changes leading to modifications in metabolism. Examples of hydrophobic primary messengers are Explain what are their general chemical properties. AL) thyroxine (tyrosine-derived hormone) and insulin (a small peptide hormone) AP) auxins (tryptophan-derived plant hormones) Answer: Explanation: 12. Which statement regarding cell-surface receptors is correct? AQ) lon-channel-coupled receptors alter the membrane potential directly by changing the permeability of the plasma…