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- One step in the synthesis of lisinopril, a drug used to treat high blood pressure, involves the reaction of A with B in the presence of a reducing agent to form C. What is the structure of C?Provide the required information for the reaction scheme below: OH Compound B Compound C OH Compound A CHO CH2OH CHO CH2OH Compound E Compound DPredict the product
- The major product formed in the reaction below is:Consider the reaction sequence below to answer the following questions: L. NaOE, EOH CO NaO, OH Compound Z 2. Co Compound X Compeund YThioglycolic acid, HSCH2CO2H, a substance used in depilatory agents (hair removers) has pKa = 3.42. What is the percent dissociation of thioglycolic acid in a buffer solution at pH = 3.0?
- The double bond of an enamine (alkene + amine) is much more nucleophilic than a typical alkene double bond. Assuming that the nitrogen atom in an enamine is sp2hybridized, draw an orbital picture of an enamine, and explain why the double bond is electron-rich.8.57 Predict the major product(s) for each of the following reactions: H2 (PPh3)3RhCI ? (a) (b) ? (c) (d) 1) BH3⚫ THF 2) H2O2, NaOH 1) RCO3H 2) H3O+ ? H3O+ ?In which orbital is the lone pair electron of pyrrole nitrogen present? (A) sp (B) sp (C) sp (D) p