13. Given the following interactions, what is the difference in the amount of strain associated with the conformations shown? Me/Me gauche: 0.9 kcal/mol Me/H 1,3-diaxial: 0.9 kcal/mol OH/H 1,3-diaxial: 0.25 kcal/mol F (A) OH (B) Me Me Me (A) 0.4 kcal/mol (B) 0.9 kcal/mol (C) 1.3 kcal/mol (D) 1.8 kcal/mol 14. Which structure represents the most stable conformation of trans-1-chloro-3-fluorocyclohexane if the F/H and CV/H 1,3-diaxial interactions are 0.12 and 0.25 kcal/mol, respectively? (C) ring inversion F HO, Me Me (D) Me

13. Given the following interactions, what is the difference in the amount of strain associated with the conformations shown? Me/Me gauche: 0.9 kcal/mol Me/H 1,3-diaxial: 0.9 kcal/mol OH/H 1,3-diaxial: 0.25 kcal/mol F (A) OH (B) Me Me Me (A) 0.4 kcal/mol (B) 0.9 kcal/mol (C) 1.3 kcal/mol (D) 1.8 kcal/mol 14. Which structure represents the most stable conformation of trans-1-chloro-3-fluorocyclohexane if the F/H and CV/H 1,3-diaxial interactions are 0.12 and 0.25 kcal/mol, respectively? (C) ring inversion F HO, Me Me (D) Me

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter19: Carboxylic Anhydrides, Esters, And Amides

Section: Chapter Questions

Problem 19.47P

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