13- If you were to have a mythical AA basedon Aspartic acid in which the carboxylate onthe side chain is replaced by a hydroxyl(alcoholic) group with pKa of 15.0. Whatwould be the predominant form of this AA atpH 1, 7 and 12?Draw ALL structures with the correct netcharges.

Amino acids are the molecules that contain amino and carboxylic acid group. When both these groups…

Answered: 13- If you were to have a mythical AA…

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

Explain why the pI of lysine is the average of the pKa values of its two protonated amino groups.
4. Proteases are enzymes that catalyze the hydrolysis of peptide bonds in proteins. The enzyme trypsin is a protease that specifically hydrolyzes only those peptide bonds that are formed by the carboxyl group of basic amino acid residues. Trypsin is present in the small intestine where it functions at an optimum pH of 8. Consider the pentapeptide Phe-His-Val-Lys-Glu. Draw the structures of the products formed from trypsin-catalyzed hydrolysis of this peptide.
n5of 15 > Glycine is a diprotic acid, which can potentially undergo two dissociation reactions, one for the a-amino group (–NH;), and the other for the carboxyl (–COOH) group. Therefore, it has two pK, values. The carboxyl group has a pKj of 2.34 and the a-aminc group has a pK2 of 9.60. Glycine can exist in fully deprotonated (NH, –CH, –COO"), fully protonated (NH† –CH, -COOH), or zwitterionic form (NH;-CH,-CO0-). Match the pH values with the corresponding form of glycine that would be present in the highest concentration in a solution of that pH. fully deprotonated form fully protonated form zwitterionic form NH,–CH,-COO" NH; –CH,-COOH NH -CH, -COO- Answer Bank pH 7.0 pH 1.0 pH 8.0 pH 11.9 PН 6.0 MacBook Air DII DD F4 F5 F6 F7 F8 F9 F10 F11 F12 $ & * 4 5 6. 7 8. R T. Y U %D F H J K + || * 00 %24
L Chapter 10-aleo-Clipboard 481-BETA-100% File Edit View Adjust Canvas Select Paint Panel Settings Help Tool S Line Esc: smooth e e = Brush Options Color 1 4.3 px 100% Draw the organic products you would expect to isolate from the following reactions (after hydrolysis). ů (a) (d) CH₂Mgl + (g) 2 Ph-MgBr + (i) (k) (m) MgBr H₂C (0) LACC H MgBr + H₂C=O + OH H Å CH₂-C-OCH, (1) BH, THF (2) H₂O₂. "OH CH₂CH₂CH (b) (e) + LIAIH HCO₂H H₂O+ MgCl CHO (h) 2 () (1) (n) + + NaBH4 H₂C H CH₂ ayahan, C -OCH, Mgl c) CH,…CH + Ph—CHO CH₂₁ 0 MẠC + Ph—Ca H Ph-MgBr + CH₂CH₂CH₂ + NaBH₂ (1) Hg(OAc)₂, H₂0 (2) NaBH₂ cold, dilute KMnO "OH Ph 100% (p) (CH₂=CH)₂CuLi + CH₂CH₂CH=CHCH₂Br Ph D Undo C Redo Select -O-X B Napolion View Layers 4:08 PM 4/27/2020
Of two possible structures A and B for the conjugate acid of guanidine, the more stable is the one that is better stabilized by electron delocalization. Which one is it? Write resonance structures showing this electron delocalization. :NH : ΝΗ +NH2 + H2N NH, NH3 H2ÑN NH, Guanidine A В
Draw the product that valine forms when it reacts with CH3COCl, pyridine; then H2O. You do not have to consider stereochemistry. Do not draw organic or inorganic by-products. Draw the product in neutral form unless conditions are clearly designed to give an ionic product. Include cationic counter-ions, e.g., Na+ in your answer, but draw them in their own sketcher. Do not include anionic counter-ions, e.g., I-, in your answer.
Draw the product that valine forms when it reacts with di-tert-butyl dicarbonate and triethylamine followed by an aqueous acid wash. O • You do not have to consider stereochemistry. • Do not draw organic or inorganic by-products. • Draw the product in neutral form unless conditions are clearly designed to give an ionic product. • Include cationic counter-ions, e.g., Na+ in your answer, but draw them in their own sketcher. • Do not include anionic counter-ions, e.g., I, in your answer. 90.0 ChemDoodle /n [F
The shaded area in the following diagram shows CH₂ CH | H CO-H-N N-H-O -CH₂ C-OH-N Gly 193 H RN Covalent bond formation between a catalytic amino acid residue and the substrate during chymotrypsin catalysis. Acid-base catalysis by a catalytic residue in chymotrypsin. Oxyanion hole which stabilizes substrate binding in chymotrypsin catalysis. Oxyanion hole which stabilizes transition state in chymotrypsin catalysis. Low barrier hydrogen bond formation between the transition state and one of the catalytic residues of chymotrypsin. ?
Treatment of pentanedioic (glutaric) anhydride with ammonia at elevated temperature leads to a compound of molecular formula C5H7NO2. What is the structure of this product? [Hint: You need to think about the reactivity not only of acid anhydrides but also of amides and carboxylic acids]
1. Write the equation of the reaction of oxidative deamination of alanine (in vitro). Specify the conditions of its passage. Name the reaction product. 2. Which of the following formulas of aspartic acid will prevail at pH = 12? Write the equation of dissociation of this acid. HOOC-CH2-CH-COO HOOC-CH2-CH-COOH *NH3 *NH3 1) HOOC-CH2-CH-COO OOC-CH₂-CH-COO™ NH₂ NH₂ 3) 2)
Complete the structures of these two am ino acids at the pH values given. Explain why the structures change at different pH values. ÇH3 H2N- -COOH H2N-C СООН H H alanine glycine at pH 1 at pH 7 at pH 14
Among these protein assays, which work in acidic conditions? a. Biuret assay b. Bicinchoninic acid assay c. Bradford assay d. Lowry assay

SEE MORE QUESTIONS

Recommended textbooks for you

Chemistry

ISBN:

9781305957404

Author:

Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:

Cengage Learning

Chemistry

ISBN:

9781259911156

Author:

Raymond Chang Dr., Jason Overby Professor

Publisher:

McGraw-Hill Education

Principles of Instrumental Analysis

Chemistry

ISBN:

9781305577213

Author:

Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Publisher:

Cengage Learning

Chemistry

ISBN:

9781305957404

Author:

Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:

Cengage Learning

Chemistry

ISBN:

9781259911156

Author:

Raymond Chang Dr., Jason Overby Professor

Publisher:

McGraw-Hill Education

Principles of Instrumental Analysis

Chemistry

ISBN:

9781305577213

Author:

Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Publisher:

Cengage Learning

Organic Chemistry

Chemistry

ISBN:

9780078021558

Author:

Janice Gorzynski Smith Dr.

Publisher:

McGraw-Hill Education

Chemistry: Principles and Reactions

Chemistry

ISBN:

9781305079373

Author:

William L. Masterton, Cecile N. Hurley

Publisher:

Cengage Learning

Elementary Principles of Chemical Processes, Bind…

Chemistry

ISBN:

9781118431221

Author:

Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard

Publisher:

WILEY

SEE MORE TEXTBOOKS

13- If you were to have a mythical AA based on Aspartic acid in which the carboxylate on the side chain is replaced by a hydroxyl (alcoholic) group with pKa of 15.0. What would be the predominant form of this AA at pH 1, 7 and 12?