12. Give the product of the following reaction CH,Br NaSH Br

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### Chemistry Reaction Problem

**Problem:**

12. Give the product of the following reaction

**Diagram:**

- **Reactant:** A benzene ring with two substituents:
  - A bromomethyl (CH2Br) group attached to one carbon atom.
  - A bromine (Br) atom attached to a carbon adjacent to the bromomethyl group.
- **Reagent:** NaSH (sodium hydrosulfide).

The skeletal structure of the reactant indicates that it is 1-bromo-2-(bromomethyl)benzene. The directed arrow indicates that the reaction proceeds with NaSH.

**Explanation of Reaction:**

In this reaction, sodium hydrosulfide (NaSH) acts as a nucleophile. It is likely to participate in a nucleophilic substitution reaction (S_N2 type) with the bromomethyl group, resulting in the substitution of the bromine atom by a thiol (–SH) group.

**Expected Product:**

The product is expected to be 2-bromobenzyl thiol (1-bromo-2-(thiomethyl)benzene), where the bromomethyl group (–CH2Br) is replaced by a thiomethyl group (–CH2SH), while the bromine atom on the benzene ring remains intact.

So the product's structure will be:

- A benzene ring with:
  - A thiomethyl (CH2SH) group attached to one carbon atom.
  - A bromine (Br) atom attached to a carbon adjacent to the thiomethyl group.

This can be abbreviated as 1-bromo-2-(thiomethyl)benzene.

This transformation highlights a common method for introducing a thiol group into an organic molecule using NaSH as a nucleophile.
Transcribed Image Text:### Chemistry Reaction Problem **Problem:** 12. Give the product of the following reaction **Diagram:** - **Reactant:** A benzene ring with two substituents: - A bromomethyl (CH2Br) group attached to one carbon atom. - A bromine (Br) atom attached to a carbon adjacent to the bromomethyl group. - **Reagent:** NaSH (sodium hydrosulfide). The skeletal structure of the reactant indicates that it is 1-bromo-2-(bromomethyl)benzene. The directed arrow indicates that the reaction proceeds with NaSH. **Explanation of Reaction:** In this reaction, sodium hydrosulfide (NaSH) acts as a nucleophile. It is likely to participate in a nucleophilic substitution reaction (S_N2 type) with the bromomethyl group, resulting in the substitution of the bromine atom by a thiol (–SH) group. **Expected Product:** The product is expected to be 2-bromobenzyl thiol (1-bromo-2-(thiomethyl)benzene), where the bromomethyl group (–CH2Br) is replaced by a thiomethyl group (–CH2SH), while the bromine atom on the benzene ring remains intact. So the product's structure will be: - A benzene ring with: - A thiomethyl (CH2SH) group attached to one carbon atom. - A bromine (Br) atom attached to a carbon adjacent to the thiomethyl group. This can be abbreviated as 1-bromo-2-(thiomethyl)benzene. This transformation highlights a common method for introducing a thiol group into an organic molecule using NaSH as a nucleophile.
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