11. INTERPRET THE DATA Phosphofructokinase is an enzyme that acts on fructose 6- phosphate at an early step in glucose breakdown. Regulation of this enzyme controls whether the sugar will continue on in the glycolytic pathway. Considering this graph, under which condition is phosphofructokinase more active? Given what you know about glycolysis and regulation of metabolism by this enzyme, explain the mechanism by which phosphofructokinase activity differs depending on ATP concentration. Explain why it makes sense that regulation of this enzyme has evolved so that it works this way.
11. INTERPRET THE DATA Phosphofructokinase is an enzyme that acts on fructose 6- phosphate at an early step in glucose breakdown. Regulation of this enzyme controls whether the sugar will continue on in the glycolytic pathway. Considering this graph, under which condition is phosphofructokinase more active? Given what you know about glycolysis and regulation of metabolism by this enzyme, explain the mechanism by which phosphofructokinase activity differs depending on ATP concentration. Explain why it makes sense that regulation of this enzyme has evolved so that it works this way.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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11. INTERPRET THE DATA Phosphofructokinase is an enzyme that acts on fructose 6-
phosphate at an early step in glucose breakdown. Regulation of this enzyme controls
whether the sugar will continue on in the glycolytic pathway. Considering this graph,
under which condition is phosphofructokinase more active? Given what you know about
glycolysis and regulation of metabolism by this enzyme, explain the mechanism by which
phosphofructokinase activity differs depending on ATP concentration. Explain why it
makes sense that regulation of this enzyme has evolved so that it works this way.
Low ATP
concentration
High ATP
concentration
Fructose 6-phosphate
concentration
Phosphofructokinase
activity
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