10. In serine protease mechanism, which specie(s) act(s) as a nucleophile? serine histidine both serine and water water With Inhibitor max Normal max init 1/2 V Normal 1/V, maк With Inhibitor 1/N init max 1/2 V max 1/V max -1/Km [S] 1/[S] Vmax is reduced with an inhibitor however the Km remains the same

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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In serine protease mechanism, which specie(s) act(s) as a nucleophile?

A.) serine

B.) histidine

C.) both serine and water

D.) water

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10. In serine protease mechanism, which specie(s) act(s) as a nucleophile?
serine
histidine
both serine and water
water
With Inhibitor
max
Normal
max
init 1/2 V
Normal
1/V,
maк
With Inhibitor
1/N
init
max
1/2 V
max
1/V
max
-1/Km
[S]
1/[S]
Vmax is reduced with an inhibitor however the Km remains the same
Transcribed Image Text:10. In serine protease mechanism, which specie(s) act(s) as a nucleophile? serine histidine both serine and water water With Inhibitor max Normal max init 1/2 V Normal 1/V, maк With Inhibitor 1/N init max 1/2 V max 1/V max -1/Km [S] 1/[S] Vmax is reduced with an inhibitor however the Km remains the same
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