nicate the target organs of calcitriol; vrite a scheme for the calcitriol synthesis; lescribe the mechanism of calcitriol action on target cells:
nicate the target organs of calcitriol; vrite a scheme for the calcitriol synthesis; lescribe the mechanism of calcitriol action on target cells:
Chapter12: Cpt Surgery Ii
Section: Chapter Questions
Problem 1MC
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Question
![10. A 55-year-old woman presented to the hospital with complaints of muscle
weakness, fatigue, night cramps, pain in the lumbar region. When fluoroscopy
revealed a decrease in bone density, a violation of bone structure. The patient
was diagnosed with osteoporosis («porous bones»). Osteoporosis is a common
cause of fractures of the spine, femur and forearm bones. The doctor prescribed
treatment with calcitriol and calcium supplements. Calcitriol receptors exist in
two allelic variants B and b. Studies have shown that dominant homozygotes
BB are more susceptible to osteoporosis and this patient has this genotype.
What are the other causes of osteoporosis and what is the mechanism of the
therapeutic effect of calcitriol? For answer:
a) indicate the target organs of calcitriol;
b) write a scheme for the calcitriol synthesis;
c) describe the mechanism of calcitriol action on target cells;](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F92664775-ac11-449a-8575-ecb0d5969d92%2F61c1f565-fabb-4957-8759-4059c35b0e1d%2Fiz9c94_processed.jpeg&w=3840&q=75)
Transcribed Image Text:10. A 55-year-old woman presented to the hospital with complaints of muscle
weakness, fatigue, night cramps, pain in the lumbar region. When fluoroscopy
revealed a decrease in bone density, a violation of bone structure. The patient
was diagnosed with osteoporosis («porous bones»). Osteoporosis is a common
cause of fractures of the spine, femur and forearm bones. The doctor prescribed
treatment with calcitriol and calcium supplements. Calcitriol receptors exist in
two allelic variants B and b. Studies have shown that dominant homozygotes
BB are more susceptible to osteoporosis and this patient has this genotype.
What are the other causes of osteoporosis and what is the mechanism of the
therapeutic effect of calcitriol? For answer:
a) indicate the target organs of calcitriol;
b) write a scheme for the calcitriol synthesis;
c) describe the mechanism of calcitriol action on target cells;
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