1.The specific rotation of a sample of mandelic acid [PhCH(OH)CO2H] is -9.48° and of pure S-(-)- mandelic acid is -158°. Calculate the (1) % optical purity, (2) ee, (3) % composition
1.The specific rotation of a sample of mandelic acid [PhCH(OH)CO2H] is -9.48° and of pure S-(-)- mandelic acid is -158°. Calculate the (1) % optical purity, (2) ee, (3) % composition
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Question
1.The specific rotation of a sample of mandelic acid
[PhCH(OH)CO2H] is -9.48° and of pure S-(-)-
mandelic acid is -158°. Calculate the (1) % optical
purity, (2) ee, (3) % composition and (4) draw a
clear stereo-structure for S-(-)-mandelic acid.
2. Explain each of the following concepts:
a)positional isomerism
b) Newman projection formula
c) Chemoselectivity
3. use the molecular formula C4H8O2 to illustrate the
following isomers:
a) (+)-gauche and antiperiplanar
b) chain isomer
c) Enantiomer
d) Cis-and Trans cycloalkanes
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