1. Why is it that Individuals with thiamin deficiency have high levels of pyruvate in their blood?

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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ACTIVITY 10.4.2
Explain your answer briefly but concisely.
1. Why is it that Individuals with thiamin deficiency have high
levels of pyruvate in their blood?
2. How would riboflavin deficiency affect the functioning of
the tricarboxylic acid cycle?
3. Mammalian liver can carry out gluconeogenesis using
oxaloacetate as the starting material. Would the operation
of the citric acid cycle be affected by the extensive use of
oxaloacetate for gluconeogenesis? Explain your answer.
Transcribed Image Text:ACTIVITY 10.4.2 Explain your answer briefly but concisely. 1. Why is it that Individuals with thiamin deficiency have high levels of pyruvate in their blood? 2. How would riboflavin deficiency affect the functioning of the tricarboxylic acid cycle? 3. Mammalian liver can carry out gluconeogenesis using oxaloacetate as the starting material. Would the operation of the citric acid cycle be affected by the extensive use of oxaloacetate for gluconeogenesis? Explain your answer.
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