1. Which amino acids would most likely be found in the transmembrane spanning region of an integral membrane protein A. Lysine B. Alanine C. Asparagine D. Isoleucine

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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1. Which amino acids would most likely be found in the transmembrane spanning region of an
integral membrane protein
A. Lysine
B. Alanine
C. Asparagine
D. Isoleucine
2. What type of experiment was used to determine the secretory pathway went from
endoplasmic reticulum to Golgi to secretory vesicles to secreted proteins.
3. What protein helps guides free ribosomes complexed with mRNA being translated to the
rough ER?
4. In mammals, most proteins are transferred into the endoplasmic reticulum post-translationally.
True or false.
5. Misfolded glycoproteins in the endoplasmic reticulum can either be refolded correctly or
targeted for degradation with the help of what to chaperone proteins?
6. Extra credit. An emerging strain of the fungus Candida (C. guzis) is able to cause serious
infections in humans because it overexpresses a heat shock (chaperone) protein. Most Candida
species do not grow well at body temperature and don't cause serious disease. Can you think of
some ways that the overexpression of this heat shock protein allows this fungus to cause deadly
infections?
Transcribed Image Text:1. Which amino acids would most likely be found in the transmembrane spanning region of an integral membrane protein A. Lysine B. Alanine C. Asparagine D. Isoleucine 2. What type of experiment was used to determine the secretory pathway went from endoplasmic reticulum to Golgi to secretory vesicles to secreted proteins. 3. What protein helps guides free ribosomes complexed with mRNA being translated to the rough ER? 4. In mammals, most proteins are transferred into the endoplasmic reticulum post-translationally. True or false. 5. Misfolded glycoproteins in the endoplasmic reticulum can either be refolded correctly or targeted for degradation with the help of what to chaperone proteins? 6. Extra credit. An emerging strain of the fungus Candida (C. guzis) is able to cause serious infections in humans because it overexpresses a heat shock (chaperone) protein. Most Candida species do not grow well at body temperature and don't cause serious disease. Can you think of some ways that the overexpression of this heat shock protein allows this fungus to cause deadly infections?
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