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1. What are the normal morphology of the different white blood cells? 2. Give examples of atypicsl or abnormal WBCs and in what medical/physiological conditions are they observed 3. Provide examples of cytochemical stsins to visualize and study WBC's.

1. What are the normal morphology of the different white blood cells? 2. Give examples of atypicsl or abnormal WBCs and in what medical/physiological conditions are they observed 3. Provide examples of cytochemical stsins to visualize and study WBC's.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Part I. (Cite the references) What are the normal morphology of the different white blood cells? <cytoplasm, nucleus, size> Give examples of atypicsl or abnormal WBCs and in what medical/physiological conditions are they observed 3. Provide examples of cytochemical stsins to visualize and study WBC's. 1. 2. Part II. True or False 1. 2. 3. Neutrophils usually become increased in response to viral and bacterial infections. 4. Leukocyte esterases are found in monocytes and neutrophils in varying concentrations. 5. Leukocyte alkaline phosphatase (LAP) is expected to be high in leukemic cells. 6. The reference values of total WBC in adults is 4,000-10,000 cells/cumm. 7. In manual counting of WBC, the diluent used is 0.9% NSS. 8. There are 4 tertiary squares used count the WBC's. 9. Nuclear hyper-segmentation of PM's is observed in megaloblastic anemia. 10. When assessing the bone marrow cellularity, the ratio of stem cells to the stromal cells (e.g., adipocytes) should be checked. Part III. 1. 2. All the White Blood Cells are derived from myeloid stem cell. The average diameter of a WBC is 7-15um, except for the monocyte which can have a diameter as large as 30um, hence making it the largest WBC. N 7. Reference values of each type of WBC: Neutrophil Lymphocvte Monocyte Eosinphil Basophil 3. The following cells were counted in INCC: W1= 45, W2=60, W3=77, W4-50. Compute for the total 4. WBC count. Show your calculations. Is the result normal? (yes or no) 5. Different White Blood Cell disorders and anomalies (qualitative and quantitative) 6. Review classification of leukemias Special laboratory tests for leukemia assessment/diagnosis Draw the squares used in the manual estimation of White Blood Cells using the improved neubauer chamber. How many squares should be counted? Show the formula for computing the total WBC count. If nucleated RBCs are seen, what is the formula for corrected WBC count?
Transcribed Image Text:Part I. (Cite the references) What are the normal morphology of the different white blood cells? <cytoplasm, nucleus, size> Give examples of atypicsl or abnormal WBCs and in what medical/physiological conditions are they observed 3. Provide examples of cytochemical stsins to visualize and study WBC's. 1. 2. Part II. True or False 1. 2. 3. Neutrophils usually become increased in response to viral and bacterial infections. 4. Leukocyte esterases are found in monocytes and neutrophils in varying concentrations. 5. Leukocyte alkaline phosphatase (LAP) is expected to be high in leukemic cells. 6. The reference values of total WBC in adults is 4,000-10,000 cells/cumm. 7. In manual counting of WBC, the diluent used is 0.9% NSS. 8. There are 4 tertiary squares used count the WBC's. 9. Nuclear hyper-segmentation of PM's is observed in megaloblastic anemia. 10. When assessing the bone marrow cellularity, the ratio of stem cells to the stromal cells (e.g., adipocytes) should be checked. Part III. 1. 2. All the White Blood Cells are derived from myeloid stem cell. The average diameter of a WBC is 7-15um, except for the monocyte which can have a diameter as large as 30um, hence making it the largest WBC. N 7. Reference values of each type of WBC: Neutrophil Lymphocvte Monocyte Eosinphil Basophil 3. The following cells were counted in INCC: W1= 45, W2=60, W3=77, W4-50. Compute for the total 4. WBC count. Show your calculations. Is the result normal? (yes or no) 5. Different White Blood Cell disorders and anomalies (qualitative and quantitative) 6. Review classification of leukemias Special laboratory tests for leukemia assessment/diagnosis Draw the squares used in the manual estimation of White Blood Cells using the improved neubauer chamber. How many squares should be counted? Show the formula for computing the total WBC count. If nucleated RBCs are seen, what is the formula for corrected WBC count?
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