1. Synthesis of Aldehydes: A. B. C. Oxidation of 1° alcohol to an aldehyde Reagents: (i) Pyridinium chlorochromate (PCC)- Shop et ex epidehode Reagents: (ii) Dess-Martin Periodinane; CH₂Cl₂ Ozonolysis of Alkenes to aldehydes/ketones Reagents: 03; then Zn, H3O+
1. Synthesis of Aldehydes: A. B. C. Oxidation of 1° alcohol to an aldehyde Reagents: (i) Pyridinium chlorochromate (PCC)- Shop et ex epidehode Reagents: (ii) Dess-Martin Periodinane; CH₂Cl₂ Ozonolysis of Alkenes to aldehydes/ketones Reagents: 03; then Zn, H3O+
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
Related questions
Concept explainers
Organomagnesium compounds
The interaction of alkyl halide with Mg metal in a suitable ether solvent is the common method for the synthesis of the Grignard reagent.
Hydrolysis Grignard Reactions and Reduction
Organomagnesium halides are Grignard reagents. Francois Auguste Victor Grignard, a French chemist who received the Nobel Prize in Chemistry in 1912, created these highly useful reagents.
Question
Can you provide the mechanism and explain with an example for those reagents?
![1. Synthesis of Aldehydes:
8
B.
C.
& Ketones Synthesis
A. Oxidation of 1° alcohol to an aldehyde
D
PA
Reagents: (i) Pyridinium chlorochromate (PCC)-> top
Reagents: (ii) Dess-Martin Periodinane; CH₂Cl₂
B.
C.
Ozonolysis of Alkenes to aldehydes/ketones
Reagents: 03; then Zn, H3O+
II. Synthesis of Ketones
A. Oxidation of 2° alcohol to a ketone
Reagents: Jones Reagent (CrO3 in aquous H₂SO4; acetone)
Reagents: Pyridinium chlorochromate (PCC)
Reagents: Dess-Martin Periodinane: CH₂Cl₂
Reagents: K₂Cr₂O7 in aquous H₂SO4
pidehode
Red
M
Partial Reduction of Esters to an aldehyde
Relagents: Diisobutyl aluminum hydride (DIBAH) in toluene, -78 °C, then
H3O+
Reduction of Acid chloride to an aldehyde (Rosenmund Reduction)
Reagents H₂, Pd, BaSO4
D.
E. Reagnets: KMnO4, heat
F.
Reagents: Ozonolysis of Alkenes to aldehydes/ketones
G. Reagents: Oxymercuration of terminal and internal alkynes; HgSO4,
H₂SO4, H2₂O
H. Reagents: Friedel-Crafts Acylation (Electrohilic Aromatic Substitution);
RC(O)CI, AICI 3](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F637a8243-98d2-45ca-8dd1-4e9d7d0f97ca%2F95549626-6505-4620-a9aa-916c19e65abe%2Fm96adi_processed.jpeg&w=3840&q=75)
Transcribed Image Text:1. Synthesis of Aldehydes:
8
B.
C.
& Ketones Synthesis
A. Oxidation of 1° alcohol to an aldehyde
D
PA
Reagents: (i) Pyridinium chlorochromate (PCC)-> top
Reagents: (ii) Dess-Martin Periodinane; CH₂Cl₂
B.
C.
Ozonolysis of Alkenes to aldehydes/ketones
Reagents: 03; then Zn, H3O+
II. Synthesis of Ketones
A. Oxidation of 2° alcohol to a ketone
Reagents: Jones Reagent (CrO3 in aquous H₂SO4; acetone)
Reagents: Pyridinium chlorochromate (PCC)
Reagents: Dess-Martin Periodinane: CH₂Cl₂
Reagents: K₂Cr₂O7 in aquous H₂SO4
pidehode
Red
M
Partial Reduction of Esters to an aldehyde
Relagents: Diisobutyl aluminum hydride (DIBAH) in toluene, -78 °C, then
H3O+
Reduction of Acid chloride to an aldehyde (Rosenmund Reduction)
Reagents H₂, Pd, BaSO4
D.
E. Reagnets: KMnO4, heat
F.
Reagents: Ozonolysis of Alkenes to aldehydes/ketones
G. Reagents: Oxymercuration of terminal and internal alkynes; HgSO4,
H₂SO4, H2₂O
H. Reagents: Friedel-Crafts Acylation (Electrohilic Aromatic Substitution);
RC(O)CI, AICI 3
Expert Solution
![](/static/compass_v2/shared-icons/check-mark.png)
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 4 steps with 5 images
![Blurred answer](/static/compass_v2/solution-images/blurred-answer.jpg)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Recommended textbooks for you
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781305957404/9781305957404_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781259911156/9781259911156_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
![Principles of Instrumental Analysis](https://www.bartleby.com/isbn_cover_images/9781305577213/9781305577213_smallCoverImage.gif)
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781305957404/9781305957404_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
![Chemistry](https://www.bartleby.com/isbn_cover_images/9781259911156/9781259911156_smallCoverImage.gif)
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
![Principles of Instrumental Analysis](https://www.bartleby.com/isbn_cover_images/9781305577213/9781305577213_smallCoverImage.gif)
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
![Organic Chemistry](https://www.bartleby.com/isbn_cover_images/9780078021558/9780078021558_smallCoverImage.gif)
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
![Chemistry: Principles and Reactions](https://www.bartleby.com/isbn_cover_images/9781305079373/9781305079373_smallCoverImage.gif)
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
![Elementary Principles of Chemical Processes, Bind…](https://www.bartleby.com/isbn_cover_images/9781118431221/9781118431221_smallCoverImage.gif)
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY