Chapter22: Organic And Biological Molecules
Section: Chapter Questions
Problem 162MP
Related questions
Question
For 1 and 2, provide a mechanistic explanation for the following observation:
1. Acid chlorides undergo reaction with Grignard reagents at room temperature to form a tertiary alcohol.
2. Treatment of an α,β-unsaturated carbonyl compound with a base yields an anion by removal of H+ from
the γ carbon. Why are the hydrogens on this carbon acidic?

Transcribed Image Text:1.
OH
R-C-R
+ R-MgX
R
CI
R

Transcribed Image Text:2.
-CH=CH-CH3
-CH=CH-CH2
base
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