1.     In 2010, investigators were interested in studying early-adult obesity as a risk factor for cancer mortality. The in­vestigators obtained physician health reports on students who attended the University of Glasgow between 1948 and 1968. These reports included records of the students’ heights and weights at the time they attended the university. The students were then followed through 2010. Mortality information was obtained using death certificates. This study can best be described as a: a.      Nested case-control b.     Cross-sectional c.      Prospective cohort d.     Retrospective cohort e.      Population-based case-control 2.     From 1983 to 1988, blood samples were obtained from 3,450 HIV-negative men in the Multicenter AIDS Cohort Study (MACS) and stored in a national repository. In 2010 a researcher was interested in examining the associa­tion between levels of inflammation and HIV infection. Of the 3,450 men, 660 men were identified as HIV-infected cases. The researcher investigated the association between C-reactive protein (CRP) and HIV infection among these 660 cases and 660 controls, matched to the cases by age and ethnicity, who did not become infected with HIV. The researcher used the stored blood samples to measure the serum level of CRP, a marker of systemic inflammation. The study initiated in 2010 is an example of a: a.      Nested case-cohort study b.     Nested case-control study c.      Retrospective cohort study d.     Cross-sectional study e.      Randomized clinical trial 3.     Suppose that a small, randomized, single-masked experimental study is conducted. Which of the following problems are surely avoided in this study? a.      Noncompliance b.     Confounding c.      Biased assessment of the disease outcome d.     Loss to follow-up 4.     Suppose that a randomized intervention study of vitamin D supplementation for the prevention of prostate cancer was conducted among White men aged 50–64 years living in the United States. The results of this study are most generalizable to which of the following groups? a.      While Men aged 50–64 years living in the United kingdom b.     White Men aged 65–85 living in the United States. c.      Black men aged 50–64 years living in the United States State whether or not a cohort study is best suited for each of the following scenarios: 5.     When little is known about a rare exposure 6.     When little is known about a rare disease 7.     When the study population will be difficult to follow 8.     When you want to learn about multiple effects of an exposure

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1.     In 2010, investigators were interested in studying early-adult obesity as a risk factor for cancer mortality. The in­vestigators obtained physician health reports on students who attended the University of Glasgow between 1948 and 1968. These reports included records of the students’ heights and weights at the time they attended the university. The students were then followed through 2010. Mortality information was obtained using death certificates. This study can best be described as a: a.      Nested case-control b.     Cross-sectional c.      Prospective cohort d.     Retrospective cohort e.      Population-based case-control 2.     From 1983 to 1988, blood samples were obtained from 3,450 HIV-negative men in the Multicenter AIDS Cohort Study (MACS) and stored in a national repository. In 2010 a researcher was interested in examining the associa­tion between levels of inflammation and HIV infection. Of the 3,450 men, 660 men were identified as HIV-infected cases. The researcher investigated the association between C-reactive protein (CRP) and HIV infection among these 660 cases and 660 controls, matched to the cases by age and ethnicity, who did not become infected with HIV. The researcher used the stored blood samples to measure the serum level of CRP, a marker of systemic inflammation. The study initiated in 2010 is an example of a: a.      Nested case-cohort study b.     Nested case-control study c.      Retrospective cohort study d.     Cross-sectional study e.      Randomized clinical trial 3.     Suppose that a small, randomized, single-masked experimental study is conducted. Which of the following problems are surely avoided in this study? a.      Noncompliance b.     Confounding c.      Biased assessment of the disease outcome d.     Loss to follow-up 4.     Suppose that a randomized intervention study of vitamin D supplementation for the prevention of prostate cancer was conducted among White men aged 50–64 years living in the United States. The results of this study are most generalizable to which of the following groups? a.      While Men aged 50–64 years living in the United kingdom b.     White Men aged 65–85 living in the United States. c.      Black men aged 50–64 years living in the United States State whether or not a cohort study is best suited for each of the following scenarios: 5.     When little is known about a rare exposure 6.     When little is known about a rare disease 7.     When the study population will be difficult to follow 8.     When you want to learn about multiple effects of an exposure
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