1. For the structure below, assign the chiral centers with R/S configurations. Draw an enantiomer and diastereomer. Convert the original structure to Fischer Projection. OH H HO NH₂ ㅎ.......

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**Stereochemistry and Fischer Projections**

1. For the structure below, assign the chiral centers with R/S configurations. Draw an enantiomer and diastereomer. Convert the original structure to Fischer Projection.

**Image Description of Chemical Structure:**
The chemical structure shown is a molecule featuring two chiral centers. The structure includes the following:
- A carboxyl group (COOH) on the right side attached to a carbon.
- An amino group (NH₂) on the left side of another carbon.
- A hydroxyl group (OH) attached to the central carbon atom, which has four different substituents (implying a chiral center).
- Another hydroxyl group attached to the second carbon atom on the upper side (again, suggesting a second chiral center).

The chiral centers should be assigned R or S configurations based on the priority rules in the Cahn–Ingold–Prelog priority system.

**Diagrams Explanation:**
1. **Stereochemistry**: Each of the chiral centers will have specific configurations (R or S). Configuration is determined by assigning priorities to the attached substituents based on atomic numbers, then orienting the molecule so that the lowest priority substituent is directed away from the viewer and determining the order of the remaining substituents.

2. **Enantiomer**: This is a non-superimposable mirror image of the original molecule. Swapping the configurations (R becomes S, and S becomes R) would give the enantiomer.

3. **Diastereomer**: This is not a mirror image and not superimposable on the original molecule. It can be obtained by changing the configuration of one chiral center while keeping the other constant.

4. **Fischer Projection**: Fischer projections are a two-dimensional representation of the molecule where the chiral carbon atoms are represented as intersections of horizontal and vertical lines. In the Fischer projection:
   - Horizontal lines represent bonds coming out of the plane towards the viewer.
   - Vertical lines represent bonds going behind the plane away from the viewer.

Using Fischer projections helps easily visualizing and comparing the stereochemistry of chiral molecules.
Transcribed Image Text:**Stereochemistry and Fischer Projections** 1. For the structure below, assign the chiral centers with R/S configurations. Draw an enantiomer and diastereomer. Convert the original structure to Fischer Projection. **Image Description of Chemical Structure:** The chemical structure shown is a molecule featuring two chiral centers. The structure includes the following: - A carboxyl group (COOH) on the right side attached to a carbon. - An amino group (NH₂) on the left side of another carbon. - A hydroxyl group (OH) attached to the central carbon atom, which has four different substituents (implying a chiral center). - Another hydroxyl group attached to the second carbon atom on the upper side (again, suggesting a second chiral center). The chiral centers should be assigned R or S configurations based on the priority rules in the Cahn–Ingold–Prelog priority system. **Diagrams Explanation:** 1. **Stereochemistry**: Each of the chiral centers will have specific configurations (R or S). Configuration is determined by assigning priorities to the attached substituents based on atomic numbers, then orienting the molecule so that the lowest priority substituent is directed away from the viewer and determining the order of the remaining substituents. 2. **Enantiomer**: This is a non-superimposable mirror image of the original molecule. Swapping the configurations (R becomes S, and S becomes R) would give the enantiomer. 3. **Diastereomer**: This is not a mirror image and not superimposable on the original molecule. It can be obtained by changing the configuration of one chiral center while keeping the other constant. 4. **Fischer Projection**: Fischer projections are a two-dimensional representation of the molecule where the chiral carbon atoms are represented as intersections of horizontal and vertical lines. In the Fischer projection: - Horizontal lines represent bonds coming out of the plane towards the viewer. - Vertical lines represent bonds going behind the plane away from the viewer. Using Fischer projections helps easily visualizing and comparing the stereochemistry of chiral molecules.
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