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1. Electrophilic aromatic substitution of benzene will not proceed without Lewis acid catalyst. Give the reagent (including catalyst) and the product for the following reactions of benzene. a. Nitration b. Chlorination C. Alkylation d. Acylation e. Sulfonation

1. Electrophilic aromatic substitution of benzene will not proceed without Lewis acid catalyst. Give the reagent (including catalyst) and the product for the following reactions of benzene. a. Nitration b. Chlorination C. Alkylation d. Acylation e. Sulfonation

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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at Tools Table Window Help )) 59% Document1 References Mailings Review View Aa AaBbCcDdEe AaBbCcDdEe AABBCCDC AaBbc Normal No Spacing Heading 1 Heac PLS 1A (Group 5) Module 4A: Friedel-Crafts acylation: synthesis of 1-(p-tolyl)ethenone 1. Electrophilic aromatic substitution of benzene will not proceed without Lewis acid catalyst. Give the reagent (including catalyst) and the product for the following reactions of benzene. a. Nitration b. Chlorination C. Alkylation d. Acylation e. Sulfonation 2. Show the Friedel-Crafts acylation reaction of anisole and nitrobenzene with acetic anhydride? Explain the different products formed. 3. What is the basis in the separation of the components of a mixture in chromatography? 4. Describe in detail the five basic steps in the thin layer chromatographic (TLC) separation. 5. What is the difference between Rf value and retention time (RT)? 6. The chromatogram represents the separation of the components of a mixture after development. Calculate the Rf values of the three components of sample X in the chromatogram. If the SP is silica gel C-18, which is the polar component and the nonpolar component? E Focus MAY 11 J P
Transcribed Image Text:at Tools Table Window Help )) 59% Document1 References Mailings Review View Aa AaBbCcDdEe AaBbCcDdEe AABBCCDC AaBbc Normal No Spacing Heading 1 Heac PLS 1A (Group 5) Module 4A: Friedel-Crafts acylation: synthesis of 1-(p-tolyl)ethenone 1. Electrophilic aromatic substitution of benzene will not proceed without Lewis acid catalyst. Give the reagent (including catalyst) and the product for the following reactions of benzene. a. Nitration b. Chlorination C. Alkylation d. Acylation e. Sulfonation 2. Show the Friedel-Crafts acylation reaction of anisole and nitrobenzene with acetic anhydride? Explain the different products formed. 3. What is the basis in the separation of the components of a mixture in chromatography? 4. Describe in detail the five basic steps in the thin layer chromatographic (TLC) separation. 5. What is the difference between Rf value and retention time (RT)? 6. The chromatogram represents the separation of the components of a mixture after development. Calculate the Rf values of the three components of sample X in the chromatogram. If the SP is silica gel C-18, which is the polar component and the nonpolar component? E Focus MAY 11 J P
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