Give the major organic product of the following reactions (a-e). ### Reaction Schemes for Chemical TransformationsBelow are various organic reactions depicting the transformation of different carbonyl compounds using specific reagents and conditions.#### a) Ester Reduction- **Substrate:** Methyl butanoate- **Reagents and Conditions:** 1. **DIBAL-H, -78°C** 2. Water (H₂O)- **Transformation:** The ester group is reduced, typically to an aldehyde, under these conditions.#### b) Imine Formation- **Substrate:** Cyclohexanone- **Reagents:** - Dimethylamine (CH₃NHCH₃) - Trace acid (H⁺)- **Transformation:** The ketone undergoes nucleophilic addition with the amine to form an imine.#### c) Diester Reduction- **Substrate:** Methyl acetoacetate (a β-keto ester)- **Reagents and Conditions:** 1. Excess Lithium Aluminium Hydride (LiAlH₄) 2. Acidic workup (H₃O⁺)- **Transformation:** The β-keto ester is completely reduced to the corresponding alcohols.#### d) Reductive Amination- **Substrate:** 2-Hexanone- **Reagents:** - Methylamine (CH₃NH₂) - Trace acid (H⁺) - Sodium cyanoborohydride (NaBH₃CN)- **Transformation:** The ketone is converted into an amine via reductive amination.#### e) Imine Formation with Benzaldehyde- **Substrate:** Benzaldehyde- **Reagents:** - Ethylamine (CH₃CH₂NH₂) - Trace acid (H⁺)- **Transformation:** Similar to example b, the aldehyde forms an imine with the primary amine under the presence of a trace acid.These reactions demonstrate common transformations in organic synthesis, particularly involving carbonyl compounds and their reactions with metal hydrides, amines, and reducing agents.

1. DIBALH, -78°C а) OCH3 2. H,О CH3NHCH3, trace H* b) 1. excess LİAIH4 c) OCH3 2. НЗО+ d) CH3NH2, trace H*, NaBH3CN CH;CH2NH2, trace H* e) `H

1. DIBALH, -78°C а) OCH3 2. H,О CH3NHCH3, trace H* b) 1. excess LİAIH4 c) OCH3 2. НЗО+ d) CH3NH2, trace H, NaBH3CN CH;CH2NH2, trace H e) `H

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

Give the major organic product of the following reactions (a-e).

### Reaction Schemes for Chemical Transformations

Below are various organic reactions depicting the transformation of different carbonyl compounds using specific reagents and conditions.

#### a) Ester Reduction

- **Substrate:** Methyl butanoate
- **Reagents and Conditions:**
1. **DIBAL-H, -78°C**
2. Water (H₂O)
- **Transformation:** The ester group is reduced, typically to an aldehyde, under these conditions.

#### b) Imine Formation

- **Substrate:** Cyclohexanone
- **Reagents:**
- Dimethylamine (CH₃NHCH₃)
- Trace acid (H⁺)
- **Transformation:** The ketone undergoes nucleophilic addition with the amine to form an imine.

#### c) Diester Reduction

- **Substrate:** Methyl acetoacetate (a β-keto ester)
- **Reagents and Conditions:**
1. Excess Lithium Aluminium Hydride (LiAlH₄)
2. Acidic workup (H₃O⁺)
- **Transformation:** The β-keto ester is completely reduced to the corresponding alcohols.

#### d) Reductive Amination

- **Substrate:** 2-Hexanone
- **Reagents:**
- Methylamine (CH₃NH₂)
- Trace acid (H⁺)
- Sodium cyanoborohydride (NaBH₃CN)
- **Transformation:** The ketone is converted into an amine via reductive amination.

#### e) Imine Formation with Benzaldehyde

- **Substrate:** Benzaldehyde
- **Reagents:**
- Ethylamine (CH₃CH₂NH₂)
- Trace acid (H⁺)
- **Transformation:** Similar to example b, the aldehyde forms an imine with the primary amine under the presence of a trace acid.

These reactions demonstrate common transformations in organic synthesis, particularly involving carbonyl compounds and their reactions with metal hydrides, amines, and reducing agents.

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