1. Construct a pedigree chart of the trait traced in the situation below. 2. The pedigree chart must be constructed with the names and genotypes at the bottom of every individual in the chart. If it is autosomal: Always use the first letter of the dominant trait to represent the dominant allele. For example, if the dominant trait is red, so the allele R-red, while r-yellow. For example, if the person is homozygous dominant for curly hair, we write CC as his genotype. If sex-linked, do not forget to write the parents’ chromosomes (XX-female, XY-male), with their corresponding superscripts (dominant or recessive). The superscript must be based on the first letter of the disorder. For example, the mother is a carrier of hemophilia (which is x-linked recessive), so we write XHXh. If the father has hemophilia, we write XhY. Put the pedigree chart using code properly. The situation is given below: Trait: Neurofibromatosis The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. The recessive form is a normal protein - in other words, no neurofibromatosis. Situation: Karina wants to know from whom she got her disorder. Her grandmother Ana has neurofibromatosis. Ana marries Angelo, who does not have the disease. They both have children named Christine (eldest), Monica, Joseph, Marco, and Yna (youngest). Monica, Marco, and Yna have the disorder out of the five children. Christine marries a man with the disorder, and they have two daughters, Kadita and Karina, who both have the disorder, and another daughter, Karrie, who does not have neurofibromatosis. Yna, on the other hand, marries a man with the disorder. They have four children, Dianne, Danica, Dennis, and Dan. Danica and Dennis have the disorder.
1. Construct a pedigree chart of the trait traced in the situation below.
2. The pedigree chart must be constructed with the names and genotypes at the bottom of every individual in the chart.
If it is autosomal: Always use the first letter of the dominant trait to represent the dominant allele. For example, if the dominant trait is red, so the allele R-red, while r-yellow. For example, if the person is homozygous dominant for curly hair, we write CC as his genotype.
If sex-linked, do not forget to write the parents’ chromosomes (XX-female, XY-male), with their corresponding superscripts (dominant or recessive). The superscript must be based on the first letter of the disorder. For example, the mother is a carrier of hemophilia (which is x-linked recessive), so we write XHXh. If the father has hemophilia, we write XhY. Put the pedigree chart using code properly.
The situation is given below:
Trait: Neurofibromatosis
The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form.
The recessive form is a normal protein - in other words, no neurofibromatosis.
Situation:
Karina wants to know from whom she got her disorder. Her grandmother Ana has neurofibromatosis. Ana marries Angelo, who does not have the disease. They both have children named Christine (eldest), Monica, Joseph, Marco, and Yna (youngest). Monica, Marco, and Yna have the disorder out of the five children. Christine marries a man with the disorder, and they have two daughters, Kadita and Karina, who both have the disorder, and another daughter, Karrie, who does not have neurofibromatosis. Yna, on the other hand, marries a man with the disorder. They have four children, Dianne, Danica, Dennis, and Dan. Danica and Dennis have the disorder.
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