1. Compare and contrast SN1, SN2, E1 and E2 reactions. What are some obvious similarities and differences between each reaction pathway? What are the requirements for each reaction to work? Discuss why SN2 is in direct competition with E2 while SN1 is in direct competition with the E1 reaction pathway. What is the rate expression for each? Which Which reactions are step-wise? reactions are concerted? Which reactions are stereospecific and what is the stereospecificity of each that are? How do the variables below help influence which reaction pathway will lead to the major product formed? a. Substrate (substitution pattern and leaving group ability) b. Nucleophile/base strength (weak or strong) and size (unhindered or hindered) C. Solvent (polar-aprotic or polar-protic) d Temperature (low/ambient temps vs higher tampg)

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Chapter1: Chemical Foundations
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1. Compare and contrast SN1, SN2, E1 and E2 reactions. What are some obvious similarities
and differences between each reaction pathway? What are the requirements for each
reaction to work? Discuss why SN2 is in direct competition with E2 while SN1 is in direct
competition with the El reaction pathway. What is the rate expression for each? Which
Which reactions are step-wise?
reactions are concerted?
rode
Which reactions are
stereospecific and what is the stereospecificity of each that are? How do the variables
below help influence which reaction pathway will lead to the major product formed?
a. Substrate (substitution pattern and leaving group ability)
b. Nucleophile/base strength (weak or strong) and size (unhindered or hindered)
c. Solvent (polar-aprotic or polar-protic)
H
d. Temperature (low/ambient temps vs. higher temps)
Hass of bel rai
CHT
Sodio
Jan 201
impotavom musela or wolle simple ofer
100
HOOGM
08.1
Oroor
SM
o viso (
1
Transcribed Image Text:1. Compare and contrast SN1, SN2, E1 and E2 reactions. What are some obvious similarities and differences between each reaction pathway? What are the requirements for each reaction to work? Discuss why SN2 is in direct competition with E2 while SN1 is in direct competition with the El reaction pathway. What is the rate expression for each? Which Which reactions are step-wise? reactions are concerted? rode Which reactions are stereospecific and what is the stereospecificity of each that are? How do the variables below help influence which reaction pathway will lead to the major product formed? a. Substrate (substitution pattern and leaving group ability) b. Nucleophile/base strength (weak or strong) and size (unhindered or hindered) c. Solvent (polar-aprotic or polar-protic) H d. Temperature (low/ambient temps vs. higher temps) Hass of bel rai CHT Sodio Jan 201 impotavom musela or wolle simple ofer 100 HOOGM 08.1 Oroor SM o viso ( 1
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