"0.h+1.2.OHa = Electrophilic additionb = E2 EliminationCH31.Submit AnswerAICI31. aqueous NaOH2. aqueous HCIwwwOHc = SN1 Nucleophilic substitution f = Carbonyl nucleophilic addnRetry Entire GroupOH++d = $N2 Nucleophilic substitution g = Nucleophilic subs at carbonyl(acyl Xfer)e= Electrophilic aromatic substitution h = Conjugate (nucleophilic) addnIdentify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use theletters a - i for your answers.CH3OH4 more group attempts remainingHCI

Friedel-Crafts acylationHydrolysis

1. 2. a = Electrophilic addition b = E2 Elimination OH 1. CH3 N 2. AICI3 1. aqueous NaOH 2. aqueous HCI OH c = SN1 Nucleophilic substitution f = Carbonyl nucleophilic addn OH + CH3OH HCI Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for your answers. d = SN2 Nucleophilic substitution e Electrophilic aromatic substitution h = Conjugate (nucleophilic) addn g= Nucleophilic subs at carbonyl(acyl Xfer)

1. 2. a = Electrophilic addition b = E2 Elimination OH 1. CH3 N 2. AICI3 1. aqueous NaOH 2. aqueous HCI OH c = SN1 Nucleophilic substitution f = Carbonyl nucleophilic addn OH + CH3OH HCI Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for your answers. d = SN2 Nucleophilic substitution e Electrophilic aromatic substitution h = Conjugate (nucleophilic) addn g= Nucleophilic subs at carbonyl(acyl Xfer)

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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1. Br2 Br "Br CH3 Ethanol Ph. -CH3 KCI H₂O 2. H Ph KOH Ph- Ph. H H e = Electrophilic addition h = SN1 Nucleophilic substitution i = SN2 Nucleophilic substitution - j = Electrophilic aromatic substitution a = Proton transfer b = Lewis acid/base C = Radical chain substitution d = Radical chain addition f = E1 Elimination g E2 Elimination = Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - j for your answers. 1. 2.8
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3. SN2 reactions are useful in the synthesis of many pharmaceutical compounds. The antiviral agent acyclovir can be prepared using an S№2 reaction as shown below followed by a hydrolysis reaction. The hydrolysis reaction will be discussed in CHEM 40B. R'RN A + B SN2 R'RN ELECTROPHILE: من مهمه NUCLEOPHILE: Identify which molecule (A or B) would serve as the electrophile and which would serve as the nucleophile in the S№2 reaction. Place your responses in the box below. Connections to biology The amino acid cysteine is one of the common building blocks of proteins that contains the thiol (SH) functional group. The reactivity of the thiol group allows researchers to connect various molecules to proteins, a process known as labeling. For example, it is possible to connect fluorescent probes that allow us to trace the fate of proteins in the cell. H SH O Cysteine amino acid within a protein chain sa acyclovir LG H₂N S OH H O Cysteine amino acid labeled with electrophilic probe…
1. CH3 Ph oto KOH O OH Ethanol Ph Ph-H -CH₂ + KCI H₂O 2. OCOH a = Proton transfer d Radical chain addition g= E2 Elimination b= Lewis acid/base e Electrophilic addition h = SN1 Nucleophilic substitution c = Radical chain substitution f = E1 Elimination i = SN2 Nucleophilic substitution Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for your answers. 1. 2. HCI
Question 6
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Answer g,h,i parts
1. aq. NaOH reflux NaCI H20 OH 2. HI a = Proton transfer d = Radical chain addition g = E2 Elimination b = Lewis acid/base e = Electrophilic addition h = SN1 Nucleophilic substitution C = Radical chain substitution f = E1 Elimination i = SN2 Nucleophilic substitution Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for your answers. 1. 2. Submit Answer Retry Entire Group 9 more group attempts remaining
Chemistry Which of the following species are likely to be nucleophiles and which electrophiles? OH CH3O CH3CI (CH3)3N CH3CH₂ H₂C CH3 A B D E 1. electrophile II. nucleophile I < A B O O E F C H₂C=CH₂ F
Identify the mechanism by which each of the reactions above proceeds using the letters listed
Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a - i for your answers.
Chemistry 1. 2. ů. + 1. CH₂OH a= Proton transfer b= Lewis acid/base c = Radical chain substitution d Radical chain addition = 2. Aqueous acetone OCH₂ + Y HO e Electrophilic addition f E1 Elimination g = E2 Elimination HCI Identify the mechanism by which each of the reactions above proceeds from among the mechanisms listed. Use the letters a- j for your answers. h= S1 Nucleophilic substitution i= SN2 Nucleophilic substitution j= Electrophilic aromatic substitution