1) New nucleic acids are made 5' to 3'. 2) Base paired strands are antiparallel. Apply this knowledge and determine which areas on this replication bubble will have new DNA made as leading strands. (hint: Start with primers at the origin on the top and the bottom of the replication bubble.) 5' B and C A and D B and D A and B A ⒸA and C C origin origin There is no way to determine this. B D

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**Replication Bubble Analysis**

1) New nucleic acids are made 5' to 3'.

2) Base paired strands are antiparallel.

Apply this knowledge and determine which areas on this replication bubble will have new DNA made as leading strands.

*Hint: Start with primers at the origin on the top and the bottom of the replication bubble.*

**Diagram Explanation**

The diagram depicts a replication bubble with two origins of replication at the top and the bottom. The bubble is labeled with four regions: A, B, C, and D. The sequence on the left side is labeled as 5'.

**Options to Determine Leading Strands**

- ○ B and C
- ○ A and D
- ○ B and D
- ○ A and B
- ○ There is no way to determine this.
- ○ A and C

The correct option, based on the given information, is **B and C**.
Transcribed Image Text:**Replication Bubble Analysis** 1) New nucleic acids are made 5' to 3'. 2) Base paired strands are antiparallel. Apply this knowledge and determine which areas on this replication bubble will have new DNA made as leading strands. *Hint: Start with primers at the origin on the top and the bottom of the replication bubble.* **Diagram Explanation** The diagram depicts a replication bubble with two origins of replication at the top and the bottom. The bubble is labeled with four regions: A, B, C, and D. The sequence on the left side is labeled as 5'. **Options to Determine Leading Strands** - ○ B and C - ○ A and D - ○ B and D - ○ A and B - ○ There is no way to determine this. - ○ A and C The correct option, based on the given information, is **B and C**.
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