Majorr product? ### Ketone Reduction MechanismThis diagram illustrates a typical organic chemistry reaction involving the reduction of a ketone using organolithium reagents. Below is a detailed explanation of the components and steps:#### Reactants and Reagents1. **Reactant Structure:** - The reactant is a compound with an ester functional group (R-O-C(=O)-R') and a ketone functional group (R'-C(=O)-R''). - Specific structure: ethyl isobutyrate.2. **Reagents and Conditions:** - **Step 1**: Ethyl Lithium (EtLi) in excess, in diethyl ether (Et₂O) as the solvent. - **Step 2**: Water (H₂O) for quenching.#### Explanation of the Reaction Steps1. **Addition of Ethyl Lithium (EtLi):** - Ethyl lithium acts as a strong nucleophile and base, attacking the electrophilic carbonyl carbon of the ester group. - The step is performed in an anhydrous ether solvent (Et₂O) to prevent any reaction with water.2. **Quenching with Water (H₂O):** - The reaction mixture is treated with water to neutralize any remaining reactive species. This step helps in the final workup and isolation of the product.This reaction sequence typically leads to the reduction of the ester to an alcohol and further reaction due to the excess of ethyl lithium.

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Answered: 1) ELI (excess) duct? O. 2) H20

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Chemistry

1) ELI (excess) duct? O. 2) H20

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

Majorr product?

### Ketone Reduction Mechanism

This diagram illustrates a typical organic chemistry reaction involving the reduction of a ketone using organolithium reagents. Below is a detailed explanation of the components and steps:

#### Reactants and Reagents
1. **Reactant Structure:**
- The reactant is a compound with an ester functional group (R-O-C(=O)-R') and a ketone functional group (R'-C(=O)-R'').
- Specific structure: ethyl isobutyrate.

2. **Reagents and Conditions:**
- **Step 1**: Ethyl Lithium (EtLi) in excess, in diethyl ether (Et₂O) as the solvent.
- **Step 2**: Water (H₂O) for quenching.

#### Explanation of the Reaction Steps
1. **Addition of Ethyl Lithium (EtLi):**
- Ethyl lithium acts as a strong nucleophile and base, attacking the electrophilic carbonyl carbon of the ester group.
- The step is performed in an anhydrous ether solvent (Et₂O) to prevent any reaction with water.

2. **Quenching with Water (H₂O):**
- The reaction mixture is treated with water to neutralize any remaining reactive species. This step helps in the final workup and isolation of the product.

This reaction sequence typically leads to the reduction of the ester to an alcohol and further reaction due to the excess of ethyl lithium.

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