1 Antigen in excess 4 Circulating immune complexes are trapped in the vessel walls. Antigen- Antibody- Endothelial cells Clump of immune complexes of blood vessel 2 Formation of immune complexes Neutrophils are attracted and release enzymes that cause tissue damage. Immune complex Neutrophils release enzymes. Activated complement causes basophils to release inflammatory mediators that increase vascular permeability. Complement activated Basophil Mediators O FIGURE 17.5 Type III Hypersensitivity: Immune Complex-Medlated When antigen is in slight excess (1), immune complexes form (2) and activate complement, resulting in increased vascular permeability (3). Immune complexes are trapped in the blood vessels (4) and complement attracts neutrophils that release enzymes, damaging the tissue (5). Complement in the blood Spaces created by dilation of blood vessel
1 Antigen in excess 4 Circulating immune complexes are trapped in the vessel walls. Antigen- Antibody- Endothelial cells Clump of immune complexes of blood vessel 2 Formation of immune complexes Neutrophils are attracted and release enzymes that cause tissue damage. Immune complex Neutrophils release enzymes. Activated complement causes basophils to release inflammatory mediators that increase vascular permeability. Complement activated Basophil Mediators O FIGURE 17.5 Type III Hypersensitivity: Immune Complex-Medlated When antigen is in slight excess (1), immune complexes form (2) and activate complement, resulting in increased vascular permeability (3). Immune complexes are trapped in the blood vessels (4) and complement attracts neutrophils that release enzymes, damaging the tissue (5). Complement in the blood Spaces created by dilation of blood vessel
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Why do immune complexes form only when an antigen is soluble?
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