1 Active Site Reaction Mechanism Inhibitor HN- 2•Zn NH2 HO. HO, NH2 N N- NH `NH NH NH, N' 'N N 'N NH2 OH -OH OH -OH но. HO но- но. он он OH Он 'N' OH но. OH Affinity-based Transition state analog Mechanism-based Uncompetitive

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter4: Cell Structure
Section: Chapter Questions
Problem 43CTQ: Pathogenic E. coil have recently been shown to degrade tight junction proteins during infection. How...
icon
Related questions
Question

mark the mechanism of irreversible inhibition 

1
Active Site
Reaction Mechanism
Inhibitor
HN-
2+Zn
NH2
но,
HO NH2
N-
N.
N-
N-
NH
o-H
NH
NH3
NH
N°
N.
'N'
'N'
NH2
OH
OH
OH
-OH-
но
но
но.
HO
N-
OH
OH
OH
OH
OH
OH
но.
OH
Affinity-based
Transition state analog
Mechanism-based
Uncompetitive
Non-specific
Transcribed Image Text:1 Active Site Reaction Mechanism Inhibitor HN- 2+Zn NH2 но, HO NH2 N- N. N- N- NH o-H NH NH3 NH N° N. 'N' 'N' NH2 OH OH OH -OH- но но но. HO N- OH OH OH OH OH OH но. OH Affinity-based Transition state analog Mechanism-based Uncompetitive Non-specific
2
Active Site
Reaction Mechanism
Inhibitor
`NH2
н он
SH
OH
OH
OH
-OH
O.
--N.
NH
+
NH
OH
OH
`O----Mg²+
OH
-Mg²+
Uncompetitive
Affinity-based
Transition state analog
Non-specific
Mechanism-based
Transcribed Image Text:2 Active Site Reaction Mechanism Inhibitor `NH2 н он SH OH OH OH -OH O. --N. NH + NH OH OH `O----Mg²+ OH -Mg²+ Uncompetitive Affinity-based Transition state analog Non-specific Mechanism-based
Expert Solution
steps

Step by step

Solved in 4 steps

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax