1) 2,4,6-Trimethylpyridine (also called 2,4,6-collidine) (shown in figure 1) consists of a pyridine ring substituted with three methyl groups. It is often used as a buffer because of its high stability and its biologically relevant pH range. In this problem we will make a buffer with 2,4,6-collidine (pka = 7.43). H3C N. CH3 a) Typically the buffer is prepared from a 0.400M stock solution of 2,4,6-Collidine and 1.00M HCI to adjust the pH. What volume of stock and what volume of titrant would be needed to make 250ml of a buffer with 0.200M total concentration at pH = 7.25? [note: you may also use Dl water to get the correct total volume] CH3

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1) 2,4,6-Trimethylpyridine (also called 2,4,6-collidine) (shown in figure 1) consists of a pyridine ring substituted
with three methyl groups. It is often used as a buffer because of its high stability and its biologically relevant pH
range. In this problem we will make a buffer with 2,4,6-collidine (pKa = 7.43).
H3C
N
CH3
a) Typically the buffer is prepared from a 0.400M stock solution of
2,4,6-Collidine and 1.00M HCI to adjust the pH. What volume of
stock and what volume of titrant would be needed to make 250ml of
a buffer with 0.200M total concentration at pH = 7.25? [note: you
may also use Dl water to get the correct total volume]
CH3
Transcribed Image Text:1) 2,4,6-Trimethylpyridine (also called 2,4,6-collidine) (shown in figure 1) consists of a pyridine ring substituted with three methyl groups. It is often used as a buffer because of its high stability and its biologically relevant pH range. In this problem we will make a buffer with 2,4,6-collidine (pKa = 7.43). H3C N CH3 a) Typically the buffer is prepared from a 0.400M stock solution of 2,4,6-Collidine and 1.00M HCI to adjust the pH. What volume of stock and what volume of titrant would be needed to make 250ml of a buffer with 0.200M total concentration at pH = 7.25? [note: you may also use Dl water to get the correct total volume] CH3
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