FOR 560 module 3

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Arizona State University *

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560

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Statistics

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Feb 20, 2024

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FOR 560 Module 3: Assignment 1. What is the random match probability for 17,17 at D3S1358? p^2 = (0.1683)^2 = 0.0283 2. What is the random match probability for 17,17 at D3S1358 and 18,26 at FGA? 2pq = 2(0.0146)(0.0388) = 0.00113 0.0283+0.00113 = 0.02943 3. What is the random match probability for 15,16 at D3S1358, 14,14 at vWA, 10,12 at D8S1179 and 12,12 at D16S539? 4. What is the random match probability for 18,18 at D3S1358, 17,18 at vWA, 26,26 at FGA, 14,15 at D8S1179, 31,31.2 at D21S11, 19,19 at D18S51, 12,13 at D5S818, 10,11 at D13S317, 12,12 at D7S820, 12,13 at D16S539, 7,9.3 at THO1, 10,11 at TPOX, and 12,12 at CSF1PO? 5. The article lists that they tested 105 individuals to obtain allele frequencies for the population, yet they report n=103 or n=101 for the different locations. Why isn't n=105 for all of the locations? The reason for n=105 is for all of the locations, is because certain individuals may have been excluded from testing due to not meeting certain standards, such as having a uncertain genotype or rare genotype. In genetics, an allele is a option form of a gene. Another reason may be that individuals were not available for testing, which is why genotypes could not be determined. 6. Extra credit (1point). When we do random match calculations for criminal casework, typically we provide statistics for the three most common populations in the area. Why? When each individual in the three common populations when chosen at random has the same probability of being selected, without creating bias. 7. Extra credit (1 point). The random match calculation across the populations will typically vary. Why? The random match calculation will typically vary depending on the genotype frequencies at all the loci, or even how common or rare the alleles of the genotype may be.

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