Final Paper Submission- Ivadny Ochoa Rembis -2

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Jun 19, 2024

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Ochoa Rembis 1 Eliminating racial bias in health care AI: Expert panel offers guidelines Ivadny Ochoa Rembis Arizona State University MED 320 Dr. Rollin Medcalf April 14, 2024
Ochoa Rembis 2 Introduction The article "Eliminating racial bias in health care AI: Expert panel offers guidelines" published in the JAMA Network Open addresses the critical issue of bias in healthcare algorithms and offers a structured framework to mitigate these biases. It emphasizes the significant impact that bias in algorithm development and application can have on racial and ethnic minoritized groups, leading to disparities in healthcare outcomes. According to the article, “Health care algorithms, defined as mathematical models used to inform decision-making, are ubiquitous and may be used to improve health outcomes. However, algorithmic bias has harmed minoritized communities in housing, banking, and education, and health care is no different” (Marshall 2023). The panel of experts convened by the Agency for Healthcare Research and Quality and the National Institute for Minority Health and Health Disparities proposes a comprehensive approach to promote equity in healthcare through the algorithm lifecycle, from development to deployment and monitoring. The panel developed a conceptual framework that applies these principles across the algorithm's life cycle, focusing on health and healthcare equity for patients and communities within the broader context of structural racism and discrimination . The article highlights the importance of multiple stakeholders' collaboration in mitigating and preventing algorithmic bias, including problem formulation, data selection, algorithm development, deployment, and monitoring. Addressing algorithmic bias is urgent, as highlighted by a Biden Administration Executive Order aimed at preventing and remedying discrimination , including protection from algorithmic discrimination . The article provides examples of biased algorithms in healthcare that have resulted in disparities in treatment and access to services for racial and ethnic minoritized groups. To finalize, the article presents a call to action for stakeholders to implement the guiding principles and create a framework that supports health and healthcare
Ochoa Rembis 3 equity, transparency, community engagement, identification of fairness issues, and accountability in all phases of the health care algorithm life cycle. Discussion The ethical issue at the core of the article "Eliminating racial bias in health care AI: Expert panel offers guidelines" revolves around the presence and impact of racial and ethnic bias in healthcare algorithms. These biases, when embedded in algorithms used for diagnosis, treatment, prognosis, risk stratification, and allocation of healthcare resources, can lead to disparate and inequitable health outcomes for racial and ethnic minority groups. Yale School of Medicine states the following… “Artificial intelligence (AI) is revolutionizing the way clinicians make decisions about patient care. But health care algorithms that power AI may include bias against underrepresented communities and thus amplify existing racial inequality in medicine, according to a growing body of evidence” (Backman 2023). The use of biased algorithms in healthcare settings can exacerbate existing health disparities and inequalities, leading to worse outcomes for historically marginalized populations. This goes against the principle of justice in healthcare , which demands that all individuals have equal access to care and the benefits of medical advancements, regardless of their racial or ethnic background. The ethical issue also encompasses the lack of transparency and accountability in the development and deployment of healthcare algorithms . Without clear standards for transparency, it's challenging for stakeholders, including patients and healthcare providers, to understand how decisions are made by these algorithms and to trust their fairness and accuracy. This lack of transparency can undermine the ethical principle of autonomy , where patients have the right to be informed and make decisions about their healthcare based on clear, accurate, and unbiased information. The article addresses these ethical concerns by proposing a framework and guiding principles aimed
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Ochoa Rembis 4 at mitigating and preventing bias in healthcare algorithms. These principles include promoting health and healthcare equity, ensuring transparency and explainability, engaging patients and communities authentically, identifying and addressing fairness issues explicitly, and establishing accountability for outcomes. The goal is to guide the healthcare industry toward the ethical use of AI and algorithms that advance health equity rather than perpetuate disparities. Participation in unethical acts, such as the development or deployment of biased healthcare algorithms, often stems from a complex interplay of factors that can include both intentional and unintentional motives. Understanding the humanity of the situation requires examining the various incentives, pressures, and constraints that individuals and organizations might face. The pressure to quickly bring new technologies to market can lead to shortcuts in the development process, such as insufficient testing for bias across diverse populations. According to Faster Capital, “One perspective argues that profit and ethics are inherently incompatible, as the pursuit of profit often leads to unethical practices such as exploitation of labor, environmental degradation, or unethical marketing tactics” (2024). For some organizations, the potential financial gains from deploying an algorithm widely might outweigh concerns about its fairness or accuracy for all groups. The complexity of machine learning models and the challenge of working with large, heterogeneous datasets can make it difficult to detect and correct for bias. In some cases, the technical challenge of ensuring fairness may be seen as too costly or time-consuming relative to other priorities. The desire for recognition, whether in the form of academic accolades, industry leadership, or market share, can sometimes lead to overlooking ethical considerations. In large organizations, the decision-making process regarding the development and deployment of algorithms is often diffuse, involving many stakeholders with different priorities and expertise. Stakeholders
Ochoa Rembis 5 The development of laws and regulations to address biases and inequalities, especially in healthcare and technology, has often been prompted by historical events and societal shifts that highlighted systemic injustices. While the specific domain of healthcare algorithms is relatively new and thus directly corresponding laws are in their nascent stages, the broader context of healthcare, civil rights , and data protection has seen significant legislative responses to historical injustices and ethical lapses. The Tuskegee Syphilis Study: This infamous study, which ran from 1932 to 1972, involved withholding treatment from African American men who had syphilis without their informed consent to study the disease's progression. According to the Centers for Disease Control and Prevention, “The study initially involved 600 Black men – 399 with syphilis, 201 who did not have the disease. Participants' informed consent was not collected. Researchers told the men they were being treated for “bad blood,” a local term used to describe several ailments, including syphilis, anemia, and fatigue.” (Wenger 2022) The public outcry following the revelation of this study's ethical breaches led to the National Research Act of 1974 in the U.S., which established the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. The commission developed the Belmont Report, outlining basic ethical principles for research involving human subjects. Health Insurance Portability and Accountability Act (HIPAA) of 1996. While not a direct response to a single event, HIPAA was influenced by growing concerns about the privacy and security of health information in the digital age. It established national standards to protect sensitive patient health information from being disclosed without the patient's consent or knowledge. According to the Centers for Disease Control and Prevention “While the HIPAA Privacy Rule safeguards PHI, the Security Rule protects a subset of information covered by the Privacy Rule. This subset is all individually identifiable health information a covered entity creates, receives, maintains, or
Ochoa Rembis 6 transmits in electronic form. This information is called electronic protected health information, or e-PHI . The Security Rule does not apply to PHI transmitted orally or in writing.”(Centers for Disease Control and Prevention 2022). These historical contexts underscore the pattern of legislation following public recognition of systemic injustices or ethical failings. As the field of healthcare technology, particularly the use of AI and algorithms, continues to evolve, it is likely that new laws and regulations will be developed in response to emerging ethical challenges. The ongoing dialogue around algorithmic bias in healthcare suggests that this area will be a significant focus of ethical and legislative attention in the years to come, continuing the pattern of legal evolution in response to societal needs and ethical imperatives. The ethical choices surrounding the development and deployment of healthcare algorithms have significant and varied impacts on different groups within society. Racial and Ethnic Minoritized Groups: These groups are disproportionately affected by biases embedded in healthcare algorithms, which can lead to misdiagnosis, delayed treatments, or inappropriate care recommendations. For example, an algorithm that underestimates the healthcare needs of Black patients compared to White patients for the same conditions can lead to Black patients receiving less medical attention or being placed lower on waiting lists for procedures. Conclusion In conclusion, the ethical dilemmas and violations associated with the use of biased healthcare algorithms highlight significant challenges at the intersection of technology, healthcare, and ethics. These issues matter deeply because they directly impact the quality of care, equity, and trust within the healthcare system. At the heart of these dilemmas is the potential for algorithms to perpetuate and even exacerbate existing health disparities among racial and ethnic minoritized groups, thereby undermining efforts to achieve equitable healthcare
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Ochoa Rembis 7 outcomes. The significance of addressing these ethical concerns cannot be overstated. Biased algorithms can lead to misdiagnosis, inappropriate treatments, and delayed care, disproportionately affecting vulnerable populations and further entrenching systemic inequities. Beyond the immediate health impacts, these biases erode trust in healthcare institutions and technologies, potentially deterring individuals from seeking care or participating in digital health initiatives. Avoiding these violations and ethical dilemmas requires a multi-pronged approach. First, there must be an increased awareness and acknowledgment of the potential for bias within healthcare algorithms, coupled with a commitment to equity as a foundational principle in algorithm development and deployment. Developers, alongside ethicists and diverse stakeholder groups, should engage in rigorous testing and validation processes to identify and mitigate biases. This process includes ensuring that datasets are representative and that algorithms are transparent and interpretable to both healthcare providers and patients.
Ochoa Rembis 8 References Chin, M. H., Afsar-Manesh, N., Bierman, A. S., Chang, C., Colón-Rodríguez, C. J., Dullabh, P., Duran, D. G., Fair, M., Hernandez-Boussard, T., Hightower, M., Jain, A., Jordan, W. B., Konya, S., Moore, R. H., Moore, T. T., Rodriguez, R., Shaheen, G., Snyder, L. P., Srinivasan, M., & Umscheid, C. A. (2023). Guiding Principles to Address the Impact of Algorithm Bias on Racial and Ethnic Disparities in Health and Health Care. JAMA Network Open , 6 (12), e2345050. https://doi.org/10.1001/jamanetworkopen.2023.45050 CDC. (2021, May 3). Tuskegee Study - Timeline - CDC - NCHHSTP . Www.cdc.gov. https://www.cdc.gov/tuskegee/timeline.htm#:~:text=The%20study%20initially%20involved%20 600 Ethical Considerations: Balancing Profit Motive with Moral Responsibility . (n.d.). FasterCapital. https://fastercapital.com/content/Ethical-Considerations--Balancing-Profit-Motive-with-Moral-R esponsibility.html Centers for Disease Control and Prevention. (2022, June 27). Health insurance portability and accountability act of 1996 (HIPAA) . Centers for Disease Control and Prevention. https://www.cdc.gov/phlp/publications/topic/hipaa.html Backman, I. (2023, December 21). Eliminating Racial Bias in Health Care AI: Expert Panel Offers Guidelines . Medicine.yale.edu. https://medicine.yale.edu/news-article/eliminating-racial-bias-in-health-care-ai-expert-panel-offe rs-guidelines/