BIS101_MockExam

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Dec 6, 2023

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BIS 101 – Exam 0 – Mock Group Exam Directions: work in small groups, complete full exam, open notes but not open internet Strategy: look over the questions before starting to solve, make sure you at least try to answer all and prioritize the ones you know you can solve. Read the full question and make sure you understand what is being asked. Identify all components that need to be addressed in your answer. Be concise. For each of the three pedigrees below, state the most likely form of inheritance and the evidence you are using to make your decision 1.1 Form of inheritance: Evidence 1.2 Form of inheritance: Evidence 1.3 Form of inheritance: Evidence 1.4 For the Autosomal Dominant trait pedigree shown below answer the following questions: What are the genotype s of the individual indicated by the arrow (II-7) and the breeding partner (II-8)? What is the probability of II-7 and II-8 having another female offspring that is affected by the trait? Show your work.
The data in the graphs to the right show variation in a population of Darwin’s finches on Daphne Island in the Galapagos. The two graphs show the distribution of beak depths in the population before and after a major drought in 1977. For these problems, assume no migration to or from the island occurs between the times the data was collected. 2.1 Describe distribution properties before the drought (top plot, 1976). Use quantitative descriptions (e.g. numbers) and cover sample size, range/variation, and central tendencies (e.g. mean/median). 2.2 Describe the change in the properties of the distributions of beak sizes between 1976 and 1978. Make sure you include in your description anything that might be used as evidence for selection/evolution. 2.3 Describe 1) how positive selection could explain the change between 1976-1978 and covering the role of fitness, and 2) describe what the plot/distribution could like after 10 more years of drought assuming positive selection continues. the 1976 plot?
2.4 Alternatively, 1) describe how neutral selection could explain the change. 2) If neutral selection is present, describe an alternative distribution that might have been observed after the drought and finch die off. Reminder: neutral selection explains situation when trait variation has no fitness impact. 2.5 Are the data shown in the population distribution consistent with a single gene inheritance pattern? Explain/defend your response.
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Now assume that beak size (large and small) follows single gene Mendelian inheritance. Answer the questions based on the most likely results from breeding scenario shown at right. Use these facts to help: - One of parental bird is true breeding, one is not. - There is no difference in phenotype proportions between the male and female F2 birds. The F1 counts represent the total counts by phenotype across 10 clutches (sets of eggs laid in one round of breeding) from the same F0 parents. The F2 counts for the two phenotypes represent each of 10 single clutches from different pairs of male and female F1 birds. Each clutch is made up of large and small beaked birds as indicated by the top and bottom numbers. E.g. Clutch 1 is shown in box and made up of 3 large and 7 small beaked birds. 3.1 What is the most likely mode of inheritance and dominance relationship between alleles? Define nomenclature you use and follow general conventions. 3.2 What are the genotypes of the parental (F0) birds and probabilities for genotype(s) of the F1 offspring? 3 0 0 0 4 0 0 4 0 0 7 4 1 12 12 3 14 8 5 2 Clutch 1
3.3 What final haploid cell genotypes after meiosis would be produced by the F0 female? What about one mitosis? 3.4 What are the most likely genotypes of the F1 pairs that produce each of the F2 clutches shown. You should list 10 pairs, one for each clutch represented. State how confident you are for each pair and why – you can be brief here.. Hint: how strong is the evidence? 3.5 Which phenotype would you breed with an F1 to best determine the genotype of an F1? In other words, what would you use for test cross to unmask a recessive allele? 3.6 What is the probability that an F2 chick produced by mating by randomly selected F1 individuals will have a large beak? What about a small beak? Show your work.