HW9

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Dec 6, 2023

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BIOS 600 Spring 2019. Homework 9. Chapter 13.
Chapter 13. Exercises 13.4. Hypotesis: H 0 : μ 1 = μ 2 = μ 3 vs. H a : At least one of the μ i s differ R code: > group1=c(9.09,9.96,9.72,9.64,8.14) > group2=c(10.21,10.48,13.01,12.74,12.58) > group3=c(9.03,9.55,12.35,9.33,9.58) > wg=stack(list('group 1'= group1, 'group 2'= group2, 'group 3'= group3)) > dt=aov(values~ind, data = wg) > summary(dt) Df Sum Sq Mean Sq F value Pr(>F) ind 2 16.71 8.353 6.028 0.0154 * Residuals 12 16.63 1.386 --- Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 > ANNOVA Table: Sum of Squares df Mean Square F Pr(>F) Between Groups 16.71 2 8.353 1.386 0.0154 Within Groups 16.63 12 1.386 Total 33.34 14 Statistics: F stat = 1.386 with 2 (numerator) and 12 (denominator) degrees of freedom P-value is 0.0154, providing significant evidence against the H 0 ; conclude the weight gain over 1- month period in lab mice with different diet differed in at least one of the groups. Results are significantly at α=0.05. Chapter 13. Exercises 13.6. R code: > pairwise.t.test(values, ind, p.adj='bonf') Pairwise comparisons using t tests with pooled SD data: values and ind group 1 group 2 group 2 0.017 - group 3 1.000 0.089 P value adjustment method: bonferroni 1. H 0 : μ 1 = μ 2 versus H a : μ 1 ≠ μ 2 2
P-value is 0.017, providing significant evidence against the H 0 ; conclude the weight gain over 1- month period in lab mice on diet 1 differed from mice on diet 2. 2. H 0 : μ 2 = μ 3 versus H a : μ 2 ≠ μ 3 P-value is 0.089, at an alpha value of 0.05 we fail to reject the null hypothesis. There is insufficient evidence that a weight gain difference exists between mice on diet 2 vs. mice on diet 2. 3. H 0 : μ 1 = μ 3 versus H a : μ 1 ≠ μ 3 P-value is 1, at an alpha value of 0.05 we fail to reject the null hypothesis. There is insufficient evidence that a weight gain difference exists between mice on diet 1 vs. mice on diet 3. Chapter 13. Exercises 13.8. Hypotheses: H 0 : M 1 = M 2 = M 3 vs. H a : at least one M i differs R code: > kruskal.test(values~ind, data=wg) Kruskal-Wallis rank sum test data: values by ind Kruskal-Wallis chi-squared = 7.94, df = 2, p-value = 0.01887 P-value is 0.01887, providing significant evidence against the H 0 ; conclude the weight gain over 1-month period in lab mice with different diet differed in at least one of the groups. Chapter 13. Exercises 13.10. 1. R code: > cohort1=c(8.7,11.9,10) > cohort2=c(1.4,1,1.3,1,1.3,2,0.6,0.8,0.7,0.9,1.9) > cohort3=c(0.9,3.3,1.2,1.1) > mean(cohort1) [1] 10.2 > sd(cohort1) [1] 1.609348 > mean(cohort2) [1] 1.172727 > sd(cohort2) [1] 0.460632 > mean(cohort3) [1] 1.625 > sd(cohort3) [1] 1.12361 3
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Sample size Mean Standard deviation Cohort 1 3 10.2 1.609348 Cohort 2 11 1.172727 0.460632 Cohort 3 4 1.625 1.12361 Double standard deviation benchmark: largest SD/smallest SD = 1.609348/0.460632 = 3.4938 > 2. The variances are not equal. Hypotesis: H 0 : σ 2 1 = σ 2 2 = σ 2 3 versus H a : at least one of the variance differs > cohort1=c(8.7,11.9,10) > cohort2=c(1.4,1,1.3,1,1.3,2,0.6,0.8,0.7,0.9,1.9) > cohort3=c(0.9,3.3,1.2,1.1) > mlt=stack(list('cohort 1'=cohort1, 'cohort 2' = cohort2, 'cohort 3' = cohort3)) > leveneTest(values~ind, data=mlt) Levene's Test for Homogeneity of Variance (center = median) Df F value Pr(>F) group 2 1.5275 0.249 15 Test statistic, F stat = 1.5275 with p value = 0.249. At an alpha level of 0.05 we fail to reject the null hypothesis. There is insufficient evidence that the variances differ between the 3 groups. 4