PhysioEx Exercise 4 Activity 3

11/26/23, 9:32 PM PhysioEx Exercise 4 Activity 3 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex4/act3/ 1/3 PhysioEx Lab Report Exercise 4: Endocrine System Physiology Activity 3: Hormone Replacement Therapy Name: Jonathan Ascencio Date: 26 November 2023 Session ID: session-2d4406e1-6640-d99a-54f9-04384ce25597 Pre-lab Quiz Results You scored 100% by answering 4 out of 4 questions correctly. Experiment Results Predict Questions Follicle-stimulating hormone (FSH) You correctly answered: stimulates ovarian follicle development. 1 Estrogen You correctly answered: is produced by developing ovarian follicles. 2 Calcitonin You correctly answered: works against the development of osteoporosis. 3 Which of the following statements is true ? You correctly answered: The ovaries stop secreting estrogen after menopause. 4 Predict Question 1: What effect will the saline injections have on the control rat's vertebral bone density? Your answer: The saline injections will not change the rat's vertebral bone density (indicated by an unchanging T score). 1 Predict Question 2: What effect will the estrogen injections have on the estrogen-treated rat's vertebral bone density? Your answer: The estrogen injections will increase the rat's vertebral bone density (indicated by a less-negative T score). 2 Predict Question 3: What effect will the calcitonin injections have on the calcitonin-treated rat's vertebral bone density? 3

11/26/23, 9:32 PM PhysioEx Exercise 4 Activity 3 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex4/act3/ 2/3 Stop & Think Questions Experiment Data Rat Elapsed Days Saline injections Estrogen injections Calcitonin injections T score Control 7 7 0 0 -2.82 Estrogen 7 0 7 0 -1.69 Calcitonin 7 0 0 7 -2.25 Post-lab Quiz Results You scored 100% by answering 4 out of 4 questions correctly. Review Sheet Results Your answer: The calcitonin injections will increase the rat's vertebral bone density (indicated by a less-negative T score). Saline injections were used in this experiment to measure the effect of You correctly answered: a placebo on bone density. 1 In the ovariectomized rats used in this experiment You correctly answered: osteoporosis was evident prior to the injections of estrogen. 2 Injection of calcitonin into an ovariectomized rat will You correctly answered: inhibit osteoclast activity and stimulate calcium uptake and deposition in long bones. 3 As the rat's bone density increases You correctly answered: the X-ray scanning assay reports a less-negative T-score. 4 Why were ovariectomized rats used in this experiment? How does the fact that the rats are ovariectomized explain their baseline T scores? Your answer: Ovariectomized rats were used because these rats are no longer producing estrogen and will exhibit bone loss due to osteoporosis. There T scores are going to be at or below -2.5 because of the amount of bone loss they have suffered. 1 What effect did the administration of saline injections have on the control rat? How well did the results compare with your prediction? 2