week 2 bio 202 openstax assignment ch 18

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Feb 20, 2024

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BIO 202: Human Anatomy & Physiology II November 05, 2023 Week 2 OpenStax assignment answers Chapter 18 – The Cardiovascular System: Blood 1. There are values given for percent saturation, tension, and blood gas, and there are listings for different types of hemoglobin. 2. blood doping increases the number of red blood cells in a person's body, which leads to its thickening and can put a person at the risk of multiple different heart diseases including stroke, pulmonary embolism and risk of dangerous pathogens entering the body. 3. this smear is normal. blood contains around 50-70% neutrophils, 2-4% eosinophils, 1% basophils, 20-30% lymphocytes, and 2-4% monocytes. 4. the endothelium does not have access to collagen and platelet tissue factor that play an important role in the initiation of the coagulation mechanism. 5. c. blood is slightly more viscous than water. 6. b. It is the most abundant plasma protein. 7. d. immunoglobulin 8. c. platelets 9. a. It facilitates the proliferation and differentiation of the erythrocyte lineage. 10. d. all of the above 11. a. They have no nucleus. 12. c. consists of four globin proteins, each bound to a molecule of heme 13. d. copper, zinc, and vitamin B12. 14. c. macrophages 15. d. polycythemia 16. c. emigration 17. b. abundant, granular, especially effective against bacteria. 18. b. are involved with specific immune function. 19. a. basophils 20. d. platelets 21. a. vascular spasm 22. c. common pathway 23. b. inadequate production of clotting factors 24. c. agglutination 25. b. lack both antigens A and B on their erythrocytes. 26. d. an Rh− mother is carrying a second Rh+ fetus 27. The patient's blood is approx. 58% plasma (since the buffy coat is less than 1%). 28. They formed elements include erythrocytes and leukocytes, which are cells (although mature erythrocytes do not have a nucleus); however, the formed elements also include platelets, which are not true cells but cell fragments. 29. False. the buffy coat is the portion of blood that is made up of its leukocytes and platelets.
30. When disease impairs the ability of the bone marrow to participate in hemopoiesis, extramedullary hemopoiesis begins in the patient's liver and spleen. this causes the spleen to enlarge. 31. The adjective myelogenous suggests a condition originating from (generated by) myeloid cells. acute myelogenous leukemia impairs the production of erythrocytes and other mature formed elements of the myeloid stem cell lineage. lymphocytes arise from the lymphoid stem cell line. 32. She is at risk for anemia, because her unusually heavy menstrual bleeding results in excessive loss of erythrocytes each month. at the same time, her vegan diet means that she does not have dietary sources of heme iron. the non-heme iron she consumes in plant foods is not as well absorbed as heme iron. 33. Bilirubin is a breakdown product of the non-iron component of heme, which is cleaved from globin when erythrocytes are degraded. excessive erythrocyte destruction would deposit excessive bilirubin in the blood. bilirubin is a yellowish pigment, and high blood levels can manifest as yellowed skin. 34. A neutrophil count below 1800 cells per microliter is considered abnormal. thus, this patient's ANC is at the low end of the normal range and there would be no reason to delay chemotherapy. in clinical practice, most patients are given chemotherapy if their ANC is above 1000. 35. Any severe stress can increase the leukocyte count, resulting in leukocytosis. a burn is especially likely to increase the proliferation of leukocytes in order to ward off infection, a significant rick when the barrier function of the skin is destroyed. 36. When blood contacts glass, the intrinsic coagulation pathway is initiated. this leads to the common pathway, and the blood clots. within about 30 minutes, the clot begins to shrink. after an hour, it is about half of its original size. its heavier weight will cause it to fall to the bottom of the tube during centrifugation, allowing the lab technician to harvest the serum remaining at the top. 37. In a thrombotic stroke, a blood vessel to the brain has been blocked by a thrombus, an aggregation of platelets and erythrocytes within a blood vessel. a thrombolytic agent is a medication that promotes the breakup of thrombi. 38. In emergency situations, blood type O- will be infused until cross matching can be done. blood type O- is called the universal donor blood because the erythrocytes have neither A nor B antigens on their surface, and the Rh factor is negative. 39. The lab technician has not made an error. blood type AB has both A and B surface antigens, and neither anti-A nor anti-B antibodies circulating in the plasma. when anti-A antibodies (added to the first well) contact A antigens on AB erythrocytes, they will cause agglutination. similarly, when anti-B antibodies contact B antigens on Ab erythrocytes, they will cause agglutination. Reference: Betts, J. G., Desaix, P., Johnson, E. W., Johnson, J. E., Korol, O., Kruse, D., Poe, B., Wise, J., Womble, M. D., & Young, K. A. (2022b). Anatomy and physiology. (Betts et al., 2022b, Chapters -18)
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