Table of Contents 1 An Introduction to Genetics 1 Pt. 1 Heredity and the Phenotype 17 2 Cell Division and Chromosomes 18 3 Mendelian Genetics 50 4 Modification of Mendelian Ratios 79 5 Linkage, Crossing Over, and Chromosome Mapping 115 6 Recombination and Mapping in Bacteria and Bacteriophages 149 7 Extensions of Genetic Analysis 180 8 Extranuclear Inheritance 208 9 Chromosome Variation and Sex Determination 221 Pt. 2 Molecular Basis of Heredity 261 10 Structure and Analysis of DNA and RNA 262 11 DNA Replication and Recombination 298 12 Storage and Expression of Genetic Information 324 13 Proteins: The End Product of Genetic Expression 364 14 Gene Mutation, DNA Repair, and Transposable Elements 389 15 Recombinant DNA Technology 428 16 Applications of Recombinant DNA Technology 461 17 Genomic Organization of DNA 490 Pt. 3 Advanced Topics in Genetic Analysis 521 18 Regulation of Gene Expression in Bacteria and Phages 522 19 Regulation of Gene Expression in Eukaryotes 544 20 Developmental Genetics 567 21 Genetics and Cancer 591 22 Genetic Basis of the Immune Response 614 23 The Genetics of Behavior 637 24 Population Genetics 659 25 Genetics and Evolution 681 Appendix A: Experimental Methods Appendix B: Glossary Appendix C: Solutions to Selected Even-Numbered Problems and Discussion Questions Credits Index