EP CONNECT ONLINE ACCESS FOR BIOLOGY
20th Edition
ISBN: 9781260494655
Author: Raven
Publisher: MCG COURSE
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 9, Problem 2S
The sheet of cells that form the gut epithelium folds into peaks called villi and valleys called crypts. The cells within the crypt region secrete a protein, Netrin-1, that becomes concentrated within the crypts. Netrin-1 is the ligand for a receptor protein that is found on the surface of all gut epithelial cells. Netrin-1 binding triggers a signal pathway that promotes cell growth. Gut epithelial cells undergo apoptosis (cell death) in the absence of Netrin-1 ligand binding.
a. How would you characterize the type of signaling (autocrine, paracrine, endocrine) found in this system?
b. Predict where the greatest amount of cell growth and cell death would occur in the epithelium.
c. The loss of the Netrin-1 receptor is associated with some types of colon cancer. Suggest an explanation for the link between this signaling pathway and tumor formation.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Humans consider themselves amazingly clever and innovative, constantly developing "new" ways of altering the world around us. As material consumption has increased, many have turned to the ideas of recycling and reuse as a means to minimize some negative aspects of our modern consumerism. Mother Nature though is the ultimate innovator and, more importantly, the ultimate recycler.
H gene assorts independently from the I gene. Both on autosomes. One man and one woman, both of HhIAIB genotype. Determine the blood type of progeny and fractions out of 16
Alleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white
A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible. Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating.
For this exercise we will use seed and data from the F10 generation of a recombinant inbred population produced using single seed…
Chapter 9 Solutions
EP CONNECT ONLINE ACCESS FOR BIOLOGY
Ch. 9.1 - Prob. 1LOCh. 9.1 - Prob. 2LOCh. 9.2 - Prob. 1LOCh. 9.3 - Prob. 1LOCh. 9.3 - Prob. 2LOCh. 9.4 - Prob. 1LOCh. 9.4 - Describe how information crosses the membrane in...Ch. 9.4 - Prob. 3LOCh. 9.4 - Prob. 4LOCh. 9.5 - Prob. 1LO
Ch. 9.5 - Prob. 2LOCh. 9 - Paracrine signaling is characterized by ligands...Ch. 9 - Signal transduction pathways a. are necessary for...Ch. 9 - The function of a ____is to add phosphates to...Ch. 9 - Which of the following receptor types is NOT a...Ch. 9 - How does the function of an intracellular receptor...Ch. 9 - Signaling through receptor tyrosine kinases often...Ch. 9 - Prob. 7UCh. 9 - Which of the following best describes the...Ch. 9 - Prob. 1ACh. 9 - The ion Ca2+ can act as a second messenger because...Ch. 9 - Different receptors can have the same effect on a...Ch. 9 - In comparing small G proteins like Ras and GPCR...Ch. 9 - Prob. 5ACh. 9 - The receptors for steroid hormones and peptide...Ch. 9 - Describe the common features found in all examples...Ch. 9 - The sheet of cells that form the gut epithelium...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Linkage in common bean Alleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible. Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating. For this exercise we will use seed and data from the F10 generation of a recombinant inbred population…arrow_forwardAlleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible. Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating. For this exercise we will use seed and data from the F10 generation of a recombinant inbred population produced using single seed…arrow_forwardcan you help? I think its B but not surearrow_forward
- Skip to main content close Homework Help is Here – Start Your Trial Now! arrow_forward search SEARCH ASK Human Anatomy & Physiology (11th Edition)BUY Human Anatomy & Physiology (11th Edition) 11th Edition ISBN: 9780134580999 Author: Elaine N. Marieb, Katja N. Hoehn Publisher: PEARSON 1 The Human Body: An Orientation expand_moreChapter 1 : The Human Body: An Orientation Chapter Questions expand_moreSection: Chapter Questions Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,... format_list_bulletedProblem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,... See similar textbooks Bartleby Related Questions Icon Related questions Bartleby Expand Icon bartleby Concept explainers bartleby Question Draw a replication bubble with two replication forks.blue lines are DNA single strands and red lines are RNA single strands.indicate all 3' and 5’ ends on all DNA single…arrow_forwardProvide an answerarrow_forwardQuestion 4 1 pts Which of the following would be most helpful for demonstrating alternative splicing for a new organism? ○ its proteome and its transcriptome only its transcriptome only its genome its proteome and its genomearrow_forward
- What did the Cre-lox system used in the Kikuchi et al. 2010 heart regeneration experiment allow researchers to investigate? What was the purpose of the cmlc2 promoter? What is CreER and why was it used in this experiment? If constitutively active Cre was driven by the cmlc2 promoter, rather than an inducible CreER system, what color would you expect new cardiomyocytes in the regenerated area to be no matter what? Why?arrow_forwardWhat kind of organ size regulation is occurring when you graft multiple organs into a mouse and the graft weight stays the same?arrow_forwardWhat is the concept "calories consumed must equal calories burned" in regrads to nutrition?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning
Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
Biology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
QCE Biology: Introduction to Gene Expression; Author: Atomi;https://www.youtube.com/watch?v=a7hydUtCIJk;License: Standard YouTube License, CC-BY