Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

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Chapter 7, Problem 3MC

Summary Introduction

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Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

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A sample of blood was taken from the above individual and prepared for haemoglobin analysis. However, when water was added the cells did not lyse and looked normal in size and shape. The technician suspected that they had may have made an error in the protocol – what is the most likely explanation? The cell membranes are more resistant than normal. An isotonic solution had been added instead of water. A solution of 0.1 M NaCl had been added instead of water. Not enough water had been added to the red blood cell pellet. The man had sickle-cell anaemia.

With reference to their absorption spectra of the oxy haemoglobin intact line) and deoxyhemoglobin (broken line) shown in Figure 2 below, how would you best explain the reason why there are differences in the major peaks of the spectra? Figure 2. SPECTRA OF OXYGENATED AND DEOXYGENATED HAEMOGLOBIN OBTAINED WITH THE RECORDING SPECTROPHOTOMETER 1.4 Abs < 0.8 06 0.4 400 420 440 460 480 500 520 540 560 580 600 nm 1. The difference in the spectra is due to a pH change in the deoxy-haemoglobin due to uptake of CO2- 2. There is more oxygen-carrying plasma in the oxy-haemoglobin sample. 3. The change in Mr due to oxygen binding causes the oxy haemoglobin to have a higher absorbance peak. 4. Oxy-haemoglobin is contaminated by carbaminohemoglobin, and therefore has a higher absorbance peak 5. Oxy-haemoglobin absorbs more light of blue wavelengths and less of red wavelengths than deoxy-haemoglobin

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Chapter 7, Problem 3MC

Summary Introduction

Introduction:

Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

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Answer 3

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Chapter 7, Problem 3MC

Summary Introduction

Introduction:

Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

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Answer 4

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Chapter 7, Problem 3MC

Summary Introduction

Introduction:

Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

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Answer 5

Chapter 7, Problem 3MC

Summary Introduction

Introduction:

Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

Answer 6

Chapter 7, Problem 3MC

Summary Introduction

Introduction:

Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

Answer 7

Chapter 7, Problem 3MC

Summary Introduction

Introduction:

Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

Answer 8

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Answer 11

Ch. 7 - Prob. 1SA Ch. 7 - Prob. 2SA Ch. 7 - Prob. 3SA Ch. 7 - Prob. 4SA Ch. 7 - Prob. 5SA Ch. 7 - Prob. 6SA Ch. 7 - Prob. 7SA Ch. 7 - Prob. 8SA Ch. 7 - Prob. 1MC Ch. 7 - Prob. 2MC

Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

Solution Summary: The author explains that gene therapy is a treatment method in which healthy, functional genes are introduced into people with defective genes to compensate for the defective gene.

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Introduction:

Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

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Chapter 7 Solutions

Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

Solution Summary: The author explains that gene therapy is a treatment method in which healthy, functional genes are introduced into people with defective genes to compensate for the defective gene.

Concept explainers

Videos

Introduction: Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.

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Chapter 7 Solutions

Introduction:

Gene therapy is a treatment method in which a healthy, functional gene is introduced into a person having a defective, disease-causing gene, so that the functional gene can compensate for the defective gene.