The fractional saturation of hemoglobin when p O 2 is 20 torr. Concept introduction: Fractional saturation is the partial fulfillment of the allosteric sites of the protein by the ligand. The ligand in hemoglobin is oxygen. Fractional saturation (Y) is the fraction at which the protein molecules are saturated with the ligand. At Y 50 , half the protein molecules are bound to ligand and half of proteins and ligands are free, thus equilibrium is achieved. The concentration of gas is mentioned as partial pressure. Torr is the unit of measure for pressure.

Question

CH3 17. Which one of the compounds below is the HNO3 H2 1. NaNO2, HCI Br₂ 1. LiAlH4 major organic product H2SO4 Ni 2. CuCN, KCN FeBr3 2. H₂O, H+ obtained from the following series of reactions? CH3 toluene CH3 CH3 Br Br Br CH3 CH3 && Br Br NH₂ A NH₂ NH₂ B C NH₂ ΝΗΣ D E

Answer 1

Question

Chapter 7, Problem 3E

(a)

Summary Introduction

To calculate: The fractional saturation of hemoglobin when pO₂ is 20 torr.

Concept introduction: Fractional saturation is the partial fulfillment of the allosteric sites of the protein by the ligand. The ligand in hemoglobin is oxygen. Fractional saturation (Y) is the fraction at which the protein molecules are saturated with the ligand. At Y₅₀, half the protein molecules are bound to ligand and half of proteins and ligands are free, thus equilibrium is achieved. The concentration of gas is mentioned as partial pressure. Torr is the unit of measure for pressure.

(b)

Summary Introduction

To calculate: The fractional saturation of hemoglobin when pO₂ is 40 torr.

Concept introduction: Fractional saturation is the partial fulfillment of the allosteric sites of the protein by the ligand. The ligand in hemoglobin is oxygen. Fractional saturation (Y) is the fraction at which the protein molecules are saturated with the ligand. At Y₅₀, half the protein molecules are bound to ligand, and half of proteins and ligands are free, thus equilibrium is achieved. The concentration of gas is mentioned as partial pressure. Torr is the unit of measure for pressure.

(c)

Summary Introduction

To calculate: The fractional saturation of hemoglobin when pO₂ is 60 torr.

Concept introduction: Fractional saturation is the partial fulfillment of the allosteric sites of the protein by the ligand. The ligand in hemoglobin is oxygen. Fractional saturation (Y) is the fraction at which the protein molecules are saturated with the ligand. At Y₅₀, half the protein molecules are bound to ligand, and half of proteins and ligands are free, thus equilibrium is achieved. The concentration of gas is mentioned as partial pressure. Torr is the unit of measure for pressure.

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