Phlebotomy Essentials
Phlebotomy Essentials
6th Edition
ISBN: 9781451194524
Author: Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher: JONES+BARTLETT PUBLISHERS, INC.
Question
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Chapter 7, Problem 1SRQ
Summary Introduction

Introduction: Glycolysis is a cellular process in which glucose molecules are broken down to form pyruvate. An antiglycolytic agent is defined as a substance that inhibits glycolysis by blood cells.

Expert Solution & Answer
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Answer to Problem 1SRQ

Correct answer: “Sodium fluoride prevents glycolysis”. Therefore, option d. is correct.

Explanation of Solution

Reason for the correct answer:

Option d. is given as “Sodium fluoride”.

Sodium fluoride is an inorganic salt of fluoride and is the most common antiglycolytic agent that preserves glucose in the blood and prevents glycolysis. It can clot the blood by itself, but more commonly used with the ethylenediaminetetraacetic acid (EDTA) or anticoagulant potassium oxalate to provide plasma specimens.

Hence, option d. is correct.

Reasons for the incorrect answers:

Option a. is given as “EDTA”.

EDTA is not an antiglycolytic agent, it is an anticoagulant agent. Therefore, option a. in incorrect.

Option b. is given as “Heparin”.

Heparin is not an antiglycolytic agent, it is an anticoagulant agent. Therefore, option b. is incorrect.

Option c. is given as “Potassium oxalate”.

Potassium oxalate is not an antiglycolytic agent, it is an anticoagulant agent. Therefore, option c. is incorrect.

Hence, options a., b., and c. are incorrect.

Conclusion

Sodium fluoride prevents glycolysis.

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