NCLEX® PREP
1. Which of the following is/are considered to be an anabolic reaction? Select all that apply.
- a. Krebs cycle
- b. polypeptide synthesis
- c. cell assembly
- d. glycolysis

Introduction:
Anabolism is often referred to as biosynthesis. The term biosynthesis explains the formation of the molecules or the cellular structure. Energy is used in the formation of larger molecules from the smaller molecules.
Answer to Problem 1NP
Correct answer:
Polypeptide synthesis and cell assembly undergo anabolic reactions. Therefore, option (b) and (c) are correct.
Option (b) is given as “polypeptide synthesis”.
Option (c) is given as “cell assembly”.
Explanation of Solution
Justify the reasons for the correct statement:
Anabolism is the construction of a large molecule from its smaller unit molecules, polypeptides are the polymers of amino acids. Cell assembly is the group of neurons which is associated with a particular concept. With every new perception, a new nerve cell is generated.
Hence, options(b) and (c) arecorrect.
Justify the reasons for the incorrect statements:
Option (a) is given as “Krebs cycle”.
Krebs cycle is not an anabolic pathway because the intermediates of the cycles are notpolymers; they are obtained from the conversion of the substrate or by the removal of a group or attachment of a group. Hence, it is a wrong answer.
Option (d) is given as “Glycolysis”.
Glycolysis is a one-way catabolic chain reaction. Intermediates are not polymers of the substrates; they originate due to rearrangements of the functional groups or addition of some other groups. Hence, it is a wrong answer.
Hence, options (a) and(d) are incorrect.
Polypeptide synthesis and cell assembly are the examples of anabolic reactions because the formation of these molecules and cells involve the input of monomers. Krebs cycle and glycolysis are the examples of catabolic reactions.
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