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Pathogenesis of neutropenia
The Hematologic System   Name of Condition Which specific part of the body is affected? What is the pathophysiology of this condition? What are the objective/subjective signs & symptoms?     Leukemia               Lymphoma                   Anemia                   Sickle Cell Anemia                     Polycythemia
Mr. Johnson, age 57, presented to his physician with marked fatigue, nausea with occasional diarrhea, and a sore, swollen tongue. Lately he also has been experiencing a tingling feeling in his toes and a feeling of clumsiness. Microscopic examination of a blood sample indicated a reduced number of erythrocytes, many of which are megaloblasts, and a reduced number of leukocytes, including many large, hypersegmented cells. Hemoglobin and serum levels of vitamin B12 were below normal. Additional tests confirm pernicious anemia.   Discussion Questions Discuss how the gastric abnormalities contribute to vitamin B12 and iron deficiency and how vitamin B12 deficiency causes complications associated with pernicious anemia. (See Pernicious Anemia—Pathophysiology, Etiology.)
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Medical Terminology | Lesson 8 | Nervous System, Cardiorespiratory and Endocrine Anatomy Terms; Author: JJ Medicine;https://www.youtube.com/watch?v=QiivC3iLZew;License: Standard YouTube License, CC-BY