Chapter 6, Problem 202R

briefly describe the pathophysiology of leukamia

Lin, a 5-year-11-month-boy. He-had a fever 20 days ago with no obvious trigger and reached the highest oral- temperature of- 40°C, no obvious cough, runny nose, vomiting, headache, dizziness, melena, urinary frequency, urgency, and dysuria but had nose bleeding. He visited a local hospital and-underwent a blood routine test: WBC=8.7X10°L, N=21%, RBC= 3.36X10%/L, BPC=75X 10°/L, Hb=109g/L; peripheral -blood smear shows: atypical cells 29%. The local hospital suspected "infectious mononucleosis", thus intravenous ganciclovir was given and his blood was extracted to check for anti-EBV antibody simultaneously. After 6-days of intravenous ganciclovir, his body temperature still fluctuated at around: 38°C. Anti-EBVVCA-IgM(-), anti-VCA-IgG(+) 1. Do you think the doctor's diagnosis is correct? And what do you think the next step would the doctor take? 2. How long does a normal fever and infectious fever last?

Explain why it is best to defer (if possible) any invasiveprocedures in leukemic patients, including dentaltreatment, until the blood counts become normal.

The Hematologic System   Name of Condition Which specific part of the body is affected? What is the pathophysiology of this condition? What are the objective/subjective signs & symptoms?     Leukemia               Lymphoma                   Anemia                   Sickle Cell Anemia                     Polycythemia