
Concept explainers
A.
To estimate: The length of DNA strands between the replication forks in the given micrograph and the time taken until the forks 4 and 5, and forks 7 and 8 will collide with each other.
Introduction: DNA is the blueprint of life and contains genetic information. Replication of DNA is semi-conservative. It begins at certain locations on the DNA known as origins of replication having a replication fork. The two replication forks move in opposite directions from origin and separate the two DNA strands.
A.

Explanation of Solution
Refer to Fig. 6-9, “The two replication forks move away in opposite directions at each replication origin” in the textbook. The micrograph shows the scale bar for measurement of DNA strand undergoing replication. Drawing 2 shows the replication process in a fly where replication forks form. As per the scale bar, the distance between replication forks 4 and 5 is approximately 0.28 µm, that is, 280 nm. It corresponds to 824 nucleotides (280/0.34), since the distance between two bases is 0.34 nm. The replication forks in eukaryotes move at about 100 nucleotides per second. Thus, the time taken for forks 4 and 5 to collide would be about 8 seconds. As shown in the drawing, replication forks 7 and 8 would never collide as they move away from each other.
B.
To evaluate: The fraction of genome of fly shown in the given micrograph.
Introduction: DNA is the blueprint of life and contains genetic information. Replication of DNA is semi-conservative. It begins at certain locations on the DNA known as origins of replication having a replication fork. The two replication forks move in opposite directions from origin and separate the two DNA strands.
B.

Explanation of Solution
The above-mentioned micrograph shown in Fig. 6-9 represents that the length of DNA is about 1.5 µm (1500). It corresponds to 4400 nucleotides (1500/0.34), since the distance between two bases is 0.34 nm. If the fly genome has 1.8×108
The fraction of fly genome shown in the micrograph is 0.002%.
Want to see more full solutions like this?
Chapter 6 Solutions
Essential Cell Biology (fifth Edition)
- In one paragraph show how atoms and they're structure are related to the structure of dna and proteins. Talk about what atoms are. what they're made of, why chemical bonding is important to DNA?arrow_forwardWhat are the structure and properties of atoms and chemical bonds (especially how they relate to DNA and proteins).arrow_forwardThe Sentinel Cell: Nature’s Answer to Cancer?arrow_forward
- Molecular Biology Question You are working to characterize a novel protein in mice. Analysis shows that high levels of the primary transcript that codes for this protein are found in tissue from the brain, muscle, liver, and pancreas. However, an antibody that recognizes the C-terminal portion of the protein indicates that the protein is present in brain, muscle, and liver, but not in the pancreas. What is the most likely explanation for this result?arrow_forwardMolecular Biology Explain/discuss how “slow stop” and “quick/fast stop” mutants wereused to identify different protein involved in DNA replication in E. coli.arrow_forwardMolecular Biology Question A gene that codes for a protein was removed from a eukaryotic cell and inserted into a prokaryotic cell. Although the gene was successfully transcribed and translated, it produced a different protein than it produced in the eukaryotic cell. What is the most likely explanation?arrow_forward
- Molecular Biology LIST three characteristics of origins of replicationarrow_forwardMolecular Biology Question Please help. Thank you For E coli DNA polymerase III, give the structure and function of the b-clamp sub-complex. Describe how the structure of this sub-complex is important for it’s function.arrow_forwardMolecular Biology LIST three characteristics of DNA Polymerasesarrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education





