EBK BIOLOGY
5th Edition
ISBN: 9780133996807
Author: Maier
Publisher: PEARSON CUSTOM PUB.(CONSIGNMENT)
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Chapter 6, Problem 11LTB
Summary Introduction
To define:
The term protooncogene and oncogene.
Introduction:
Cancer is a disease characterized by abnormal cell division. It occurs when cells in a region of the body proliferates in an uncontrolled manner, the excess tissue that develops is called a tumor or neoplasm. The main cause of the cancer is the presence of the oncogenes in the cells.
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Describe the relationship between proto-oncogenes and oncogenes.
Describe three types of genetic changes that commonly convert aproto-oncogene to an oncogene. Explain how the genetic changesare expected to alter the activity of the gene product.
What types of functions are performed by the products of proto-oncogenes?
Chapter 6 Solutions
EBK BIOLOGY
Ch. 6 - Prob. 1LTBCh. 6 - Prob. 2LTBCh. 6 - A cell that begins mitosis with 46 chromosomes...Ch. 6 - The centromere is a region at which ___________....Ch. 6 - Prob. 5LTBCh. 6 - At metaphase of mitosis, ___________. the...Ch. 6 - Sister chromatids ___________. are two different...Ch. 6 - DNA polymerase ___________. attaches sister...Ch. 6 - Prob. 9LTBCh. 6 - Prob. 10LTB
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- describe the relationship between a proto-oncogene and an oncogene, and explain how one arises from the other. Explain how a mutation in the EGF receptor, or in a GTP- binding protein, can lead to unregulated cell division.arrow_forwardExplain what a lysogen is.arrow_forwardexplain Translocations that generate oncogenesarrow_forward
- Name the roles that Anaphase Promoting Complex protein plays.arrow_forwardWhich of the following is an example of a proto-oncogene? 1) cell cycle inhibitor 2) tumor suppressor 3) oncogene 4) repair enzyme 5) growth factor receptorarrow_forward/20. In class, we discussed diffferent types of genetic change that can cause a normal gene (proto- oncogene) to become a cancer-causing gene (oncogene), Which of the following would not be a cause? A) translocation or transposition (movement of DNA within the same genome) B) gene ampliffication (increased number of copies of a given gene) C) epigenetic change D) point mutation that changes the gene's product E) loss of telomeres during DNA replication ancer?arrow_forward
- What kind of daughter cells will result if the "Normal cell" above goes through mitosis? A) two normal cells B) two cancer cells C) two specialized cells D) one cancer cell and one normal cellarrow_forwardSuppose a gain-of-function mutation happens in an oncogene. Which of the following changes is likely to result? O a) tumor-promoting inflammation O b) evading growth suppressors Oc) sustaining proliferative signalling O d) resisting cell deatharrow_forwardTrue or false Oncogenes are gene that are normally not found in a cell and must be introduced into the DNA by some mechanism, such as a viral infection.arrow_forward
- Give one examples of mutaion?arrow_forwardWhat are the roles of cellular proto-oncogenes, and how are these roles consistent with their implication in oncogenesis?arrow_forwardProto-oncogenes can change into oncogenes that cause cancer.Which of the following best explains the presence of thesepotential time bombs in eukaryotic cells?(A) Proto-oncogenes first arose from viral infections.(B) Proto-oncogenes are mutant versions of normal genes.(C) Proto-oncogenes are genetic “junk.”(D) Proto-oncogenes normally help regulate cell division.arrow_forward
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