Chapter 6, Problem 109R

Male with a history of blistering lesions on the scalp since the neonatal period andrecurrent pyoderma. After a year and a half of life, he was admitted to a specialty clinic due togeneralized pyoderma associated with febrile illness with lymphadenopathies and abscesses on the thighs. To thephysical examination revealed coarse facies, broad forehead, infraorbital fold, presence of dark circles,low nasal bridge and hypertelorism. In addition to confluent maculopapular lesions in the neckand trunk, occipital eczema, genital gluteal hyperchromic plaque, purulent external otitis. it was triedwith antibiotics with good response, but with persistence of purulent otorrhea. The study of serum immunoglobulins IgM, IgG, IgA, complement, chemotaxis and burstRespiratory was within normal ranges. Serum IgE stood out at 56,400 IU/ml (rangenormal for age 0-90 IU/ml) and eosinophilia. At the age of 2 years 11 months he was hospitalized for genital phlegmon with a good response tocloxacillin plus…

pathophysiology meningitis vs encephalitis (etiology, clinical manifestations, inflammatory response, etc.)